3-羟基-4,4,4-三氟丁酸乙酯合成路线

372-31-6三氟乙酰乙酸乙酯+7440-06-4白金→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Chong, Joshua Anthony; Abdesaken, Fereydon; Spangler, Lori Ann; Roemmele, Renee Caroline; Stephens, Randall Wayne; Nightingale, Peter David; Hartley, David John
Patent: US6307094 B1, 2001 ;

372-31-6三氟乙酰乙酸乙酯→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Janzen, Edward G.; Zhang, Young-Kang; Arimura, Masana
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5434 - 5440

→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

TAKASAGO INTERNATIONAL CORPORATION
Patent: US2003/4362 A1, 2003 ;

75-90-12,2,2-三氟乙醛+105-36-2溴乙酸乙酯→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Ishikawa, Nobuo; Koh, Moon Gyu; Kitazume, Tomoya; Choi, Sam Kwon
Journal of Fluorine Chemistry, 1984 , vol. 24, p. 419 - 430

→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Curators of the University of Missouri; 3M Innovative Properties Company
Patent: US6458865 B2, 2002 ;

64-17-5乙醇+86884-21-13-羟基-4,4,4-三氟丁酸→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Binder; Noe; Baumann; Wildburger
Archiv der Pharmazie, 1985 , vol. 318, # 3 p. 243 - 249

→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

TAKASAGO INTERNATIONAL CORPORATION
Patent: US2003/4362 A1, 2003 ;

1522-43-6→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Ratier, Max; Pereyre, Michel; Davies, Alwyn G.; Sutcliffe, Roger
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 1907 - 1916

197850-97-8→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Xu, Chengfu; Yuan, Chengye
Tetrahedron, 2005 , vol. 61, # 8 p. 2169 - 2186

60-29-7乙醚+372-31-6三氟乙酰乙酸乙酯→372-30-53-羟基-4,4,4-三氟丁酸乙酯

参考文献

Jones
Journal of the American Chemical Society, 1948 , vol. 70, p. 143