3-氧代-3,4-二氢-2-喹喔啉甲酸乙酯合成路线 （共 19 条）
反应条件
thionyl chloride T=0 - 20°C; Inert atmosphere;
参考文献
Chiurato, Matteo; Boulahjar, Rajaa; Routier, Sylvain; Troin, Yves; Guillaumet, Gerald
Tetrahedron, 2010 , vol. 66, # 25 p. 4647 - 4653
反应条件
1: T=-10°C; 0.25 h; 2: With palladium on activated charcoal in various solvent(s) Heatingaerial oxidative aromatization; Further stages.;
参考文献
Haldar, Pranab; Dutta, Bishnupada; Guin, Joyram; Ray, Jayanta K.
Tetrahedron Letters, 2007 , vol. 48, # 33 p. 5855 - 5857
反应条件
1: T=20°C; 6 h; under vacuum; 2: aerial oxidative aromatization; Further stages.;
参考文献
Haldar, Pranab; Dutta, Bishnupada; Guin, Joyram; Ray, Jayanta K.
Tetrahedron Letters, 2007 , vol. 48, # 33 p. 5855 - 5857
参考文献
Pillai, P. Madhavan; Bhat, V. Sanjeev
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 10 p. 1024 - 1028
反应条件
1: nitrous oxide View Scheme
参考文献
Fernandes, P. S.; Sonar, T. M.
Journal of the Indian Chemical Society, 1986 , vol. 63, p. 427 - 429
参考文献
Fernandes, P. S.; Sonar, T. M.
Journal of the Indian Chemical Society, 1986 , vol. 63, p. 427 - 429
反应条件
trichlorophosphate 0.166667 h; Heating;
参考文献
Hamby, James M.; Bauer, Ludwig
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1013 - 1024
反应条件
1: 3,4-Dihydro-3-oxo-2-quinoxalinecarboxylic acid,ethyl ester With sodium hydride in N,N-dimethyl-formamide T=5 - 20°C; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
KUMIAI CHEMICAL INDUSTRY CO., LTD.; IHARA CHEMICAL INDUSTRY CO., LTD.
Patent: EP2174934 A1, 2010 ;
Location in patent: Page/Page column 174 ;
参考文献
Ohle; Gross
Chemische Berichte, 1935 , vol. 68, p. 2262,2266
反应条件
1: POCl3 2: aqueous methanol.NaCN 3: 160 °C / 1 Torr View Scheme
参考文献
Gowenlock et al.
Journal of the Chemical Society, 1945 , p. 622,625
