4-羟基吡咯并[2,3-d]嘧啶合成路线 （共 18 条）
反应条件
sodium methylate; nickel monoaluminide in methanol
参考文献
Reigan, Philip; Gbaj, Abdul; Stratford, Ian J.; Bryce, Richard A.; Freeman, Sally
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 6 p. 1248 - 1260
反应条件
hydrogenchloride T=20°C; 1 h;
参考文献
Tsytovich, A. V.; Shamshin, D. V.; Burkovskii, V. B.; Shvets, V. I.
Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 11 p. 756 - 761
Bioorganicheskaya Khimiya, 1995 , vol. 21, # 11 p. 874 - 880
反应条件
1: 64 percent / NaOEt 2: 92 percent / aq. HCl 3: 81 percent / H2 / Raney Ni View Scheme
参考文献
Tsytovich, A. V.; Shamshin, D. V.; Burkovskii, V. B.; Shvets, V. I.
Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 11 p. 756 - 761
Bioorganicheskaya Khimiya, 1995 , vol. 21, # 11 p. 874 - 880
反应条件
1: 92 percent / aq. HCl 2: 81 percent / H2 / Raney Ni View Scheme
参考文献
Diederichsen, Ulf; Schmitt, Harald W.
European Journal of Organic Chemistry, 1998 , # 5 p. 827 - 835
反应条件
oxygen T=400°C; P=760.051 Torr; 5.55556E-05 h; Inert atmospherePyrolysisGas phaseFlow reactor; Temperature;
参考文献
Kibet, Joshua K.; Khachatryan, Lavrent; Dellinger, Barry
Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 32 p. 7696 - 7704
反应条件
T=400°C; P=760.051 Torr; 5.55556E-05 h; Inert atmospherePyrolysisGas phaseFlow reactor; Temperature;
参考文献
Kibet, Joshua K.; Khachatryan, Lavrent; Dellinger, Barry
Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 32 p. 7696 - 7704
参考文献
Heinrich, Timo; Staehle, Wolfgang; Greiner, Hartmut; Blaukat, Andree
Patent: US2010/160356 A1, 2010 ;
Location in patent: Page/Page column 33 ;
参考文献
Liang, Congxin; Sun, Li; Wei, Chung Chen; Tang, Peng Cho; McMahon, Gerald; Hirth, Klaus Peter; Cui, Jingrong
Patent: US2002/183319 A1, 2002 ;
US 20020183319 A1
反应条件
1.1: 92 percent / POCl3 2.1: pyridinium bromide perbromide; AcOH / 2-methyl-propan-2-ol 2.2: 36 percent / Zn; AcOH View Scheme
参考文献
Sun; Cui, Jean; Liang, Congxin; Zhou, Yong; Nematalla, Asaad; Wang, Xueyan; Chen, Hui; Tang, Cho; Wei, James
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2153 - 2157
反应条件
tetraphosphorus decasulfide in pyridine 3 h; Heating;
参考文献
Seela, Frank; Steker, Herbert
Liebigs Annalen der Chemie, 1983 , # 9 p. 1576 - 1587
