2',4'-二羟基-2-苯基苯乙酮合成路线 (共 57 条)
反应条件
hydrogenchloride; aluminium trichloride in 1,2-dichloro-ethane
参考文献
Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara RT
Patent: US5235109 A1, 1993 ;
反应条件
boron trifluoride diethyl etherate T=80 - 90°C; Inert atmosphere;
参考文献
Lu, Tzy-Ming; Kuo, Daih-Huang; Ko, Horng-Huey; Ng, Lean-Teik
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 10027 - 10032
反应条件
water T=95 - 100°C; 1 h;
参考文献
Wu; Cole; Davidson; Blosser; Borrelli; Kinsolving; Milgate; Parker
Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 788 - 792
反应条件
zinc(II) chloride in sodium hydroxide; water
反应条件
water; sodium acetate in ethanol 5 h; Reflux;
参考文献
Narender; Reddy, K. Papi; Madhur
Synthetic Communications, 2009 , vol. 39, # 11 p. 1949 - 1956
参考文献
Journal of the American Chemical Society, , vol. 60, p. 669
Journal of the Chemical Society, , p. 1381,1387
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 240, p. 2428
反应条件
1: 78 percent / zinc chloride, HCl (g) / ethyl acetate / 6.5 h 2: 75 percent / water / 1 h / 95 - 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 5 p. 788 - 792
反应条件
KS in 1,2-dichloro-ethane T=83.7°C; Acylation; Friedel-Crafts reaction;
参考文献
Synthetic Communications, , vol. 30, # 14 p. 2479 - 2485
反应条件
pyridinium p-toluenesulfonate 0.0333333 h; microwave irradiation;
参考文献
Lamba, Mandeep S.; Makrandi, Jagdish K.
Journal of Chemical Research, 2007 , # 10 p. 585 - 586
反应条件
pyridine hydrochloride T=220°C;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 32, p. 11