1-苄基-3-甲基-4-哌啶酮合成路线 （共 18 条）
反应条件
1: 1-Phenylmethyl-piperidin-4-one With sodium hydride in tetrahydrofuran T=0°C; 0.5 h; 2: methyl iodide in tetrahydrofuran T=60°C;
参考文献
SEPRACOR INC.; BURDI, Douglas; SPEAR, Kerry, L.; HARDY, Larry, Wendell
Patent: WO2010/114971 A1, 2010 ;
Location in patent: Page/Page column 138 ;
反应条件
sodium hydride in tetrahydrofuran T=20 - 60°C; 5.08333 h;
参考文献
WO2005/26145 A2, ;
Page/Page column 102; 103 ;
参考文献
Schering Corporation
Patent: US5869488 A1, 1999 ;
US 5869488 A
反应条件
sodium hydroxide in hydrogenchloride; dichloromethane
反应条件
sodium hydroxide in dichloromethane; water
参考文献
US5869488 A1, ;
US 5869488 A
反应条件
L-Selectride in tetrahydrofuran
参考文献
US5869488 A1, ;
US 5869488 A
参考文献
US5869488 A1, ;
US 5869488 A
反应条件
palladium dihydroxide; hydrogen in ethanol P=2637.5 Torr; 24 h; Ambient temperature;
参考文献
Filer; Nugent; Huang
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 11 p. 1019 - 1027
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: EP156433 B1, 1991 ;
反应条件
ammonium acetate; sodium cyanoborohydride in methanol; sodium hydroxide
