7-硫唑嘌呤双环[4.2.0]辛烷-8-酮合成路线 （共 5 条）
反应条件
T=40°C; pH=7; 48 h; Cooling with ice;
参考文献
Liu, Runhui; Chen, Xinyu; Gellman, Samuel H.; Masters, Kristyn S.
Journal of the American Chemical Society, 2013 , vol. 135, # 44 p. 16296 - 16299
反应条件
in dichloromethane 2 h;
参考文献
Journal of the American Chemical Society, , vol. 131, # 46 p. 16779 - 16789
反应条件
1: CH2Cl2 2: Na2SO3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 20 p. 2337 - 2341
反应条件
hydrogenchloride T=20°C; 0.5 h;
参考文献
Vina, Dolores; Santana, Lourdes; Uriarte, Eugenio; Quezada, Elias; Valencia, Laura
Synthesis, 2004 , # 15 p. 2517 - 2522
反应条件
1: 62 percent / Lawesson's reagent / tetrahydrofuran
2: 77 percent
3: 69 percent / chloramine-T / ethanol / Heating
View Scheme
参考文献
Hemming, Karl; Luheshi, Abdul-Bassett N.; Redhouse, Alan D.; Smalley, Robert K.; Thompson, J. Robin; et al.
Tetrahedron, 1993 , vol. 49, # 20 p. 4383 - 4408
