4-(2-甲基[1,3]二氧戊环-2-基)丁烷-2-酮合成路线 （共 19 条）
反应条件
lithium diisopropyl amide 1.) ether, -60 deg C, 18 h, 2.) 20 deg C, 2 h, HCl; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 37, p. 307 - 310
反应条件
benzophenone 2.5 h; Irradiation; Title compound not separated from byproducts;
参考文献
Mosca, Raffaella; Fagnoni, Maurizio; Mella, Mariella; Albini, Angelo
Tetrahedron, 2001 , vol. 57, # 52 p. 10319 - 10328
反应条件
1: toluene-4-sulfonic acid / Entfernen des entstehenden Butanons 2: aqueous methanol. NaOH-solution 3: diethyl ether View Scheme
参考文献
Journal of the Chemical Society, , p. 3972,3978
反应条件
1: aqueous methanol. NaOH-solution 2: diethyl ether View Scheme
参考文献
Journal of the Chemical Society, , p. 3972,3978
参考文献
Journal of the Chemical Society, , p. 3972,3978
反应条件
sulfuric acid in water; acetone T=45°C; 4 h;
参考文献
Moreau, Jean-Louis; Couffignal, Renee
Journal of Organometallic Chemistry, 1985 , vol. 294, p. 139 - 144
反应条件
1: diethyl ether
2: NaH / tetrahydrofuran
3: aq. TFA / dioxane
4: Pd-C / toluene / Heating
View Scheme
参考文献
Carless; Fekarurrhobo
Journal of the Chemical Society - Series Chemical Communications, 1984 , vol. NO. 10, p. 667 - 668
反应条件
1: 73 percent Turnov. / diethyl ether / 2 h / 20 °C
2: 94 percent Turnov. / pyridinium p-toluene sulfonate (PPTS) / H2O / acetone / 1) 48h, ca. 20 deg C, 2) 1h, 40 deg C
View Scheme
参考文献
Troyanskii, E.I.; Mizintsev, V. V.; Lazareva, M. I.; Demchuk, D. V.; Nikishin, G. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 91 p. 1879 - 1884
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 9 p. 2044 - 2049
参考文献
Warren; Weedon
Journal of the Chemical Society, 1958 , p. 3972,3978
