8-溴-2H-1-苯并吡喃-2-酮合成路线 （共 7 条）
反应条件
ethyl (triphenylphosphoranylidene)acetate in 1-methyl-pyrrolidin-2-one T=210°C; 3 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/118130 A2, 2007 ;
Location in patent: Page/Page column 28-29 ;
反应条件
potassium acetate T=170°C; 5 h; Inert atmosphere;
参考文献
Chen, Lei; Hu, Tai-Shan; Yao, Zhu-Jun
European Journal of Organic Chemistry, 2008 , # 36 p. 6175 - 6182
反应条件
pyridine; sulfuric acid T=111°C; 0.0416667 h; Microwave irradiation;
参考文献
Bratulescu, George
Synthesis, 2008 , # 18 art. no. Z23607SS, p. 2871 - 2873
反应条件
sodium methylate; triphenylphosphine T=80 - 210°C; 4 h; Ionic liquid;
参考文献
Valizadeh, Hassan; Vaghefi, Sevil
Synthetic Communications, 2009 , vol. 39, # 9 p. 1666 - 1678
反应条件
palladium diacetate; potassium hydrogencarbonate T=140°C; Heck reaction; 0.266667 h; Microwave irradiationneat (no solvent);
参考文献
Valizadeh, Hassan; Vaghefi, Sevil
Heterocyclic Communications, 2010 , vol. 16, # 2-3 p. 113 - 120
反应条件
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium iodide in tetrahydrofuran T=-78°C; Horner-Wadsworth-Emmons reaction; 1 h; 2: With potassium hydroxide in methanol T=20°C; 0.25 h;
参考文献
Takeuchi, Yasuo; Ueda, Norihiro; Uesugi, Koji; Abe, Hitoshi; Nishioka, Hiromi; Harayama, Takashi
Heterocycles, 2003 , vol. 59, # 1 p. 217 - 224
反应条件
N,N-diethylaniline 3 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 42, # 10 p. 2170 - 2173
