2-(1-环己烯基)乙醇合成路线 （共 33 条）
反应条件
1: sodium; ethanol 2: PCl5; benzene / 0 °C / Behandlung des gebildeten 1-Chlormethyl-cyclohexens-(1) (Kp: 77grad) mit Magnesium und Aethylbromid in Aether und Kochen der erhaltenen Loesung mit Paraformaldehyd View Scheme
参考文献
Mousseron; Nguyen Phuoc Du
Bulletin de la Societe Chimique de France, 1948 , p. 91,92
反应条件
1.) lithiation Multistep reaction;
参考文献
Maclnnes, Iain; Nonhebel, Derek C.; Orzulik, Stefan T.; Suckling, Colin J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2777 - 2779
反应条件
Yield given. Multistep reaction;
参考文献
Barluenga, Jose; Alvarez, Flora; Concellon, Jose M.; Yus, Miguel
Synthesis, 1986 , # 8 p. 654 - 655
反应条件
zirconium orthophosphate Dehydration; 15 h; Heating; Product distribution; Further Variations:Reagents;
参考文献
Al-Qallaf, Fawzia A. H.; Johnstone, Robert A. W.; Liu, Jun-Yao; Lu, Ling; Whittaker, David
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 7 p. 1421 - 1423
反应条件
hydrogen; platinum(IV) oxide in methanol
参考文献
Henbest,H.B.; Millward,B.B.
Journal of the Chemical Society, 1960 , p. 3575 - 3580
反应条件
(i) TsCl, Py, (ii) CaCO3, aq. acetone; Multistep reaction;
参考文献
Hanack,M.; Schneider,H.-J.
Justus Liebigs Annalen der Chemie, 1965 , vol. 686, p. 8 - 18
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in benzene
T=0 - 20°C; Mitsunobu reaction;
参考文献
Klein, Johannes E. M. N.; Mueller-Bunz, Helge; Evans, Paul
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 5 p. 986 - 995
反应条件
1: 71 percent / pyridine / 24 h / 0 - 5 °C
2: 54 percent / NaI / acetone / 24 h / Heating
3: 94 percent / NaCN / 72 h / 80 °C
View Scheme
参考文献
LaPlante, Steven R.; Boes, Michael; Brochu, Christian; Chabot, Catherine; Coulombe, Rene; Gillard, James R.; Jakalian, Araz; Poirier, Martin; Rancourt, Jean; Stammers, Timothy; Thavonekham, Bounkham; Beaulieu, Pierre L.; Kukolj, George; Tsantrizos, Youla S.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 1845 - 1854
反应条件
1: 71 percent / pyridine / 24 h / 0 - 5 °C
2: 54 percent / NaI / acetone / 24 h / Heating
3: 94 percent / NaCN / 72 h / 80 °C
4: 59 percent / 96 percent H2SO4 / methanol / 24 h / Heating
View Scheme
参考文献
Crotti, Paolo; Badalassi, Fabrizio; Di Bussolo, Valeria; Favero, Lucilla; Pineschi, Mauro
Tetrahedron, 2001 , vol. 57, # 40 p. 8559 - 8572
反应条件
pyridine; phosphorus tribromide; Petroleum ether
T=0°C;
参考文献
Keck, Gary E.; Yates, John B.
Journal of Organic Chemistry, 1982 , vol. 47, # 18 p. 3590 - 3591
