in n-heptane boiling in heptane, heating to 200°C;;

in not given sepn. impossible; detected by NMR;

in tetrahydrofuran

in tetrahydrofuran

BuLi in diethyl ether; hexane inert atmosphere; addn. of BuLi (in hexane) to HN(i-Pr)2 (in ether), addn. of Sn-compd. (-78°C, during 5 min), warming to 25°C (over 2 h, stirring), addn. of MeLi in Et2O (-78°C); addn. to CH2Cl2 (-78°C), then addn. to water, washing of org. layer (aq. HCl, H2O), drying (MgSO4), solvent removal, chromy. (SiO2/hexane);

暂无反应条件数据

in tetrahydrofuran byproducts: Bu2SnCl2; SbCl3 was added dropwise with stirring to soln. of Sn comp. (N2 or Ar);stirring for 2 h at 25°C; evapn., washing with pentane, Soxhlet extn. with pentane; elem. anal.;

water in diethyl ether; dichloromethane under Ar, addn. of a soln. of Sn compd. (ether) to a soln. (ether) of the amide at 0°C, colour changed from yellow to green, after 1 h cooling to -78°C, addn. of a soln. of BuLi (ether) and CH2Cl2, warming to room temp., pptn., hydrolysis; extd. (ether), organic layer washed (ether, aq. NaCl), dried (Na2SO4), evapn., TLC (silica gel);

BuLi in diethyl ether; hexane inert atmosphere; addn. of BuLi (in hexane) to HN(i-Pr)2 (in ether), addn. of Sn-compd. (-78°C, during 5 min), warming to 25°C (over 2 h, stirring), addn. of MeLi in Et2O (-78°C); addn. to CH2Cl2 (-78°C), then addn. to water, washing of org. layer (aq. HCl, H2O), drying (MgSO4), solvent removal, chromy. (SiO2/hexane);

in tetrahydrofuran