3,7-二甲基辛-6-烯-1-炔-3-基乙酸酯合成路线 （共 24 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine T=20°C; 3 h;
参考文献
Fuerstner, Alois; Hannen, Peter
Chemistry - A European Journal, 2006 , vol. 12, # 11 p. 3006 - 3019
反应条件
1: 6-methyl-hept-5-en-2-one; ethynyl-magnesium bromide in tetrahydrofuran T=0°C; 0.5 h; 2: acetic anhydride in tetrahydrofuran 0.5 h;
参考文献
Justicia, Jose; Oller-Lopez, Juan L.; Campana, Araceli G.; Oltra, J. Enrique; Cuerva, Juan M.; Bunuel, Elena; Cardenas, Diego J.
Journal of the American Chemical Society, 2005 , vol. 127, # 42 p. 14911 - 14921
反应条件
1: 6-methyl-hept-5-en-2-one; sodium acetylene in tetrahydrofuran T=0°C; 0.5 h; 2: acetic anhydride in tetrahydrofuran 0.5 h;
参考文献
Justicia, Jose; Oller-Lopez, Juan L.; Campana, Araceli G.; Oltra, J. Enrique; Cuerva, Juan M.; Bunuel, Elena; Cardenas, Diego J.
Journal of the American Chemical Society, 2005 , vol. 127, # 42 p. 14911 - 14921
反应条件
sodium acetate; tungsten(VI) trioxide hydrate T=135°C; 2.5 h;
参考文献
SYMRISE GmbH and Co., KG
Patent: US2009/92725 A1, 2009 ;
Location in patent: Page/Page column 12 ;
反应条件
1: 87 percent / tetrahydrofuran / -78 - 20 °C 2: 97 percent / DMAP; Et3N / 3 h / 20 °C View Scheme
参考文献
Anjum, Shazia; Marco-Contelles, Jose
Tetrahedron, 2005 , vol. 61, # 20 p. 4793 - 4803
反应条件
methanol; sodium methylate T=20°C; 48.25 h;
参考文献
SYMRISE GmbH and Co., KG
Patent: US2009/92725 A1, 2009 ;
Location in patent: Page/Page column 12 ;
反应条件
hydrogen; Lindlar's catalyst in octane T=20°C; P=760 Torr; other solvents (ethanol, acetic acid), other catalyst (2.8percent Pd/C); dependence of reaction rate; Product distribution;
参考文献
Cerveny, Libor; Kuncova, Marcela; Ruzicka, Vlastimil
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 5 p. 1258 - 1261
反应条件
Lindlar's catalyst; hexane Hydrogenation;
参考文献
Hoffmann-La Roche
Patent: US2797235 , 1954 ;
Full Text Show Details
Ofner et al.
Ind.chim.belge Sonderband 31.Congr.int.Chim.ind.Luettich 1958 Bd.2,S.644,647
反应条件
1: 75 percent / NaBr / acetonitrile; tetrahydrofuran; H2O / 9 h / Ambient temperature; electroepoxidation
2: 20 percent / p-TsOH / CH2Cl2 / 0.5 h / Ambient temperature
3: 97 percent / H2(g), quinoline / 5percent Pd/BaSO4 / methanol / Ambient temperature
4: 44 percent / 0.5 h / 200 °C
View Scheme
参考文献
Uneyama, Kenji; Date, Takasi; Torii, Sigeru
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3160 - 3163
参考文献
Saucy et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 1945,1954
