3,3-二甲基-1-氯丁烷合成路线 （共 54 条）
反应条件
sodium; Petroleum ether anschliessend mit Kohlendioxid;
参考文献
Braendstroem
Acta Chemica Scandinavica (1947-1973), 1959 , vol. 13, p. 608
反应条件
potassium hydroxide; acetic acid in water; ethylene glycol
参考文献
The Nutrasweet Company
Patent: US6573409 B1, 2003 ;
反应条件
potassium hydroxide; potassium acetate in water
参考文献
The Nutrasweet Company
Patent: US6573409 B1, 2003 ;
反应条件
potassium iodide in dimethyl sulfoxide T=95°C; 12 h;
参考文献
Sasse, Astrid; Ligneau, Xavier; Rouleau, Agnes; Elz, Sigurd; Ganellin, C. Robin; Arrang, Jean-Michel; Schwartz, Jean-Charles; Schunack, Walter; Stark, Holger
Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 4000 - 4010
参考文献
Braendstroem
Acta Chemica Scandinavica (1947-1973), 1959 , vol. 13, p. 608
反应条件
1: (i) Mg, (ii) /BRN= 102378/ 2: PBr3 View Scheme
参考文献
Dolgii,I.E.; Meshcheryakov,A.P.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1966 , p. 1935 - 1939
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1966 , # 11 p. 2004 - 2009
反应条件
dimethyl sulfoxide; sodium bromide; zinc oxide T=135 - 140°C; 14 h;
参考文献
Guo; Sawyer; Prakash
Synthetic Communications, 2001 , vol. 31, # 21 p. 3395 - 3399
反应条件
magnesium in diethyl ether
Grignard reaction; Heating;
参考文献
Tilley, Leon J.; Shiner Jr.
Journal of Physical Organic Chemistry, 1999 , vol. 12, # 7 p. 564 - 576
反应条件
1: polyethylene glycol
2: toluene / anschliessend mit festem Kohlendioxid
View Scheme
参考文献
Braendstroem
Acta Chemica Scandinavica (1947-1973), 1959 , vol. 13, p. 608
反应条件
magnesium in diethyl ether
参考文献
Brown,P. et al.
Journal of the American Chemical Society, 1965 , vol. 87, p. 4559 - 4569
