3,3-二(4-氯苯基)丙酸合成路线 （共 21 条）
反应条件
1: 1.) Mg / 1.) ether, 2.) ether, toluene, reflux, 30 min
2: aq. H2SO4, CH3COOH / 24 h / Heating
View Scheme
参考文献
Bogeso
Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 935 - 947
反应条件
1: benzene; phosphorus (V)-oxide / Behandeln des Reaktionsprodukts mit wss. Natronlauge
2: ethanol; palladium/barium sulfate / Hydrogenation
View Scheme
参考文献
Behrens et al.
Journal of Biological Chemistry, 1948 , vol. 175, p. 771,778
反应条件
1: zinc; benzene
2: benzene; phosphorus (V)-oxide / Behandeln des Reaktionsprodukts mit wss. Natronlauge
3: ethanol; palladium/barium sulfate / Hydrogenation
View Scheme
参考文献
Behrens et al.
Journal of Biological Chemistry, 1948 , vol. 175, p. 771,778
反应条件
aluminium trichloride
参考文献
Johnston,K.M.; Shotter,R.G.
Tetrahedron, 1974 , vol. 30, p. 4059 - 4064
反应条件
2: methanol. KOH
3: copper-powder
View Scheme
参考文献
Voegtli; Laeuger
Helvetica Chimica Acta, 1955 , vol. 38, p. 46,63
反应条件
1: methanol. KOH
2: copper-powder
View Scheme
参考文献
Voegtli; Laeuger
Helvetica Chimica Acta, 1955 , vol. 38, p. 46,63
反应条件
sulfuric acid; boron trifluoride
参考文献
Bott,K.
Chemische Berichte, 1967 , vol. 100, p. 2791 - 2797
参考文献
Behrens et al.
Journal of Biological Chemistry, 1948 , vol. 175, p. 771,778
Full Text Show Details
Bergmann et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 1612,1614
参考文献
Fuson; Kozacik; Eaton
Journal of the American Chemical Society, 1933 , vol. 55, p. 3799,3802
参考文献
Fuson; Kozacik; Eaton
Journal of the American Chemical Society, 1933 , vol. 55, p. 3799,3802
