1-甲基吡咯-2-甲酸乙酯合成路线 （共 13 条）
反应条件
1 h; Heating / reflux;
参考文献
UNIVERSITY OF STRATHCLYDE
Patent: WO2008/38018 A1, 2008 ;
Location in patent: Page/Page column 57-58 ;
反应条件
1: 1-methyl-pyrrole With n-butyllithium in tetrahydrofuran T=-78 - 20°C; 14.0833 h; Inert atmosphere; 2: chloroformic acid ethyl ester in tetrahydrofuran T=0°C; 1.5 h; Inert atmosphere;
参考文献
Nadres, Enrico T.; Lazareva, Anna; Daugulis, Olafs
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 471 - 483
反应条件
in tetrahydrofuran; hexane T=0°C; 1.5 h;
参考文献
Brittain, Judith M.; Jones, R. Alan; Arques, Jose Sepulveda; Saliente, Teresa Aznar
Synthetic Communications, 1982 , vol. 12, # 3 p. 231 - 248
反应条件
1: oxalyl chloride, DMF / benzene / 2 h / 10 °C 2: Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 35, # 2 p. 975 - 995
反应条件
triethylamine in acetonitrile RefluxInert atmosphere;
参考文献
Tetrahedron Letters, , vol. 51, # 31 p. 4150 - 4152
反应条件
potassium; toluene Anschliessend Erwaermen mit CH3I;
参考文献
Bulletin of the Agricultural Chemical Society of Japan, , vol. 23, p. 165,170
Journal of the American Chemical Society, , vol. 80, p. 4749
反应条件
Ambient temperature; Yield given;
参考文献
Heterocycles, , vol. 35, # 2 p. 975 - 995
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 1430,1437
反应条件
1.) ethanol, reflux, 11 h, 2.) pyridine, reflux, irradiation, 8 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 2681 - 2685
反应条件
1: tetrahydrofuran / 65 °C 2: 160 °C View Scheme
参考文献
Taillefer, Marc; Rahier, Nicolas; Minta, Ewelina; Cristau, Henri-Jean
Phosphorus, Sulfur and Silicon and Related Elements, 2002 , vol. 177, # 6-7 p. 1847 - 1850
