4-(2-甲基-2-丙烯-1-基)氯苯合成路线 （共 7 条）
反应条件
1: C15H17ClOSi With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.5 h; Inert atmosphere; 2: 3-chloro-2-methyl-propene With copper(l) iodide; triethyl phosphite in N,N-dimethyl-formamide T=50°C; 16 h; Inert atmosphere;
参考文献
Tsubouchi, Akira; Muramatsu, Daisuke; Takeda, Takeshi
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12719 - 12722
Angew. Chem., 2013 , vol. 125, # 48 p. 12951 - 12954,4
反应条件
2,6-dimethylpyridine in methanol
参考文献
Bunnett,J.F.; Sridharan,S.
Journal of Organic Chemistry, 1979 , vol. 44, # 9 p. 1458 - 1463
反应条件
1: (i) Mg, (ii) /BRN= 635680/, (iii) SOCl2, Py 2: 2,6-lutidine / methanol View Scheme
参考文献
Bunnett,J.F.; Sridharan,S.
Journal of Organic Chemistry, 1979 , vol. 44, # 9 p. 1458 - 1463
反应条件
(i) Mg, (ii) /BRN= 878160/; Multistep reaction;
参考文献
Bernotas, Ronald C.; Thomas, Craig E.; Carr, Albert A.; Nieduzak, Thaddeus R.; Adams, Ginette; Ohlweiler, David F.; Hay, David A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 10 p. 1105 - 1110
反应条件
ammonium cerium(IV) nitrate; sodium acetate 1.) 100 deg C, 20 h, 2.) acetone, water, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bly, Robert S.; Ni, Ester K.; Tse, Albert K. K.; Wallace, Easley
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1362 - 1366
反应条件
phosphoric acid 2.) 80 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Botteghi, Carlo; Bona, Denis Dalla; Paganelli, Stefano; Marchetti, Mauro; Sechi, Barbara
Anales de Quimica, 1996 , vol. 92, # 2 p. 101 - 107
反应条件
sulfuric acid in acetic acid
参考文献
Bernotas, Ronald C.; Thomas, Craig E.; Carr, Albert A.; Nieduzak, Thaddeus R.; Adams, Ginette; Ohlweiler, David F.; Hay, David A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 10 p. 1105 - 1110
