1-(4-溴苯基)金刚烷合成路线 （共 13 条）
反应条件
potassium carbonate; palladium on activated charcoal T=120°C; 12 h;
参考文献
Braese, Stefan; Waegell, Bernard; Meijere, Armin de
Synthesis, 1998 , # 2 p. 148 - 152
反应条件
bromine in tetrachloromethane regioselective reaction;
参考文献
Inomata, Sotaro; Harada, Yusuke; Matsuoka, Shin-Ichi; Ishizone, Takashi
Tetrahedron, 2013 , vol. 69, # 15 p. 3238 - 3248
反应条件
1: 145 °C 2: aq. HCl 3: (i) aq. NaNO2, aq. H2SO4, AcOH, (ii) aq. NaBr, CuSO4, Cu, H2SO4 View Scheme
参考文献
Inomata, Sotaro; Harada, Yusuke; Matsuoka, Shin-Ichi; Ishizone, Takashi
Tetrahedron, 2013 , vol. 69, # 15 p. 3238 - 3248
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 24 h / 50 °C / |Inert atmosphere 1.2: 25 h / 0 - 50 °C / |Inert atmosphere 2.1: bromine / tetrachloromethane / 12 h / 20 °C 3.1: magnesium; ethylene dibromide / dichloromethane / |Inert atmosphere; |Reflux 4.1: bromine / tetrachloromethane View Scheme
参考文献
Inomata, Sotaro; Harada, Yusuke; Matsuoka, Shin-Ichi; Ishizone, Takashi
Tetrahedron, 2013 , vol. 69, # 15 p. 3238 - 3248
反应条件
indium(III) chloride T=35°C; Friedel-Crafts Alkylation; 24 h; Inert atmosphereDarkness; regioselective reaction;
参考文献
Mosset, Paul; Gree, Rene
Synlett, 2013 , vol. 24, # 9 art. no. ST-2013-D0140-L, p. 1142 - 1146
反应条件
in dichloromethane 50 h; Ambient temperature;
参考文献
Ohno, Masatomi; Shimizu, Kazuo; Ishizaki, Kenichi; Sasaki, Tadashi; Eguchi, Shoji
Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 729 - 733
反应条件
1: magnesium; ethylene dibromide / dichloromethane / |Inert atmosphere; |Reflux 2: bromine / tetrachloromethane View Scheme
参考文献
Inomata, Sotaro; Harada, Yusuke; Matsuoka, Shin-Ichi; Ishizone, Takashi
Tetrahedron, 2013 , vol. 69, # 15 p. 3238 - 3248
反应条件
indium tribromide T=20°C; Friedel-Crafts Alkylation; 40 h; Inert atmosphereDarkness; regioselective reaction;
参考文献
Mosset, Paul; Gree, Rene
Synlett, 2013 , vol. 24, # 9 art. no. ST-2013-D0140-L, p. 1142 - 1146
反应条件
1: aq. HCl 2: (i) aq. NaNO2, aq. H2SO4, AcOH, (ii) aq. NaBr, CuSO4, Cu, H2SO4 View Scheme
参考文献
Stetter,H. et al.
Chemische Berichte, 1964 , vol. 97, p. 3488 - 3492
反应条件
1: 145 °C 2: aq. HCl 3: (i) aq. NaNO2, aq. H2SO4, AcOH, (ii) aq. NaBr, CuSO4, Cu, H2SO4 View Scheme
参考文献
Stetter,H. et al.
Chemische Berichte, 1964 , vol. 97, p. 3488 - 3492
