2-氰基-2-苯基乙烯基乙醇合成路线 （共 9 条）
反应条件
sodium ethanolate in ethanol 12 h; Ambient temperature;
参考文献
Roose, B.; Anteunis, M. J. O.; Tavernier, D.
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 4 p. 267 - 270
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C;
参考文献
Kondo, Yuki; Tadokoro, Eriko; Matsuura, Mayuko; Iwasaki, Kyoko; Sugimoto, Yukihiro; Miyake, Hideyoshi; Takikawa, Hirosato; Sasaki, Mitsuru
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 11 p. 2781 - 2786
反应条件
1: nickel; diluted alcohol / 65 - 70 °C / Hydrogenation 2: oxalic acid; water / bei der Destillation mit Wasserdampf View Scheme
参考文献
Rupe; Knup
Helvetica Chimica Acta, 1927 , vol. 10, p. 305
反应条件
1: 1.) Conc. HCl, 2.) CH3ONa / 1.) 80 deg C, 15 min, 2.) CH3OH, reflux, 15 min. 2: 1.) 75percent H2SO4, NaNO2, 2.) 50percent aq. H3PO2 / 1.) H2O, 0 deg C, 30 min, 2.) 0 deg C, 30 min 3: NaOH / aq. ethanol / 1 h / Heating 4: Quinoleine, bronze de cuivre / 0.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, p. 443 - 445
反应条件
hydrogenchloride; 18-crown-6 ether; potassium hydroxide in water; acetonitrile Thorpe reaction; 0.333333 h;
参考文献
Shah
E-Journal of Chemistry, 2011 , vol. 8, # 1 p. 368 - 372
反应条件
1: 1.) Conc. HCl, 2.) CH3ONa / 1.) 80 deg C, 15 min, 2.) CH3OH, reflux, 15 min. 2: 1.) 75percent H2SO4, NaNO2, 2.) 50percent aq. H3PO2 / 1.) H2O, 0 deg C, 30 min, 2.) 0 deg C, 30 min View Scheme
参考文献
Kirsch, G.; Cagniat, D.; Cagniat, P.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 443 - 445
反应条件
1: 1.) Conc. HCl, 2.) CH3ONa / 1.) 80 deg C, 15 min, 2.) CH3OH, reflux, 15 min. 2: 1.) 75percent H2SO4, NaNO2, 2.) 50percent aq. H3PO2 / 1.) H2O, 0 deg C, 30 min, 2.) 0 deg C, 30 min 3: NaOH / aq. ethanol / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, p. 443 - 445
反应条件
1: 1.) Conc. HCl, 2.) CH3ONa / 1.) 80 deg C, 15 min, 2.) CH3OH, reflux, 15 min.
2: KOH / ethanol
View Scheme
参考文献
Kirsch, G.; Cagniat, D.; Cagniat, P.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 443 - 445
参考文献
Gatta, Franco; Giudice, Maria Rosaria Del; Pomponi, Massimo; Marta, Maurizio
Heterocycles, 1992 , vol. 34, # 5 p. 991 - 1004
