4-三甲基甲硅烷-3-丁炔-1-醇合成路线 （共 22 条）
反应条件
1: ethynylmethyl carbinol With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78 - 20°C; 2 h;
参考文献
Dickner, Tim; Laschat, Sabine
Advanced Synthesis and Catalysis, 2000 , vol. 342, # 8 p. 804 - 811
反应条件
1: trimethylsilylacetylene With n-butyllithium in tetrahydrofuran; hexane T=-78 - 0°C; 1 h; 2: oxirane With trimethylaluminum in tetrahydrofuran; hexane T=20°C; 24 h;
参考文献
Brummond, Kay M.; McCabe, Jamie M.
Synlett, 2005 , # 16 art. no. S06305ST, p. 2457 - 2460
反应条件
n-butyllithium; chloro-trimethyl-silane in hexane
反应条件
sulfuric acid in tetrahydrofuran; chloro-trimethyl-silane
反应条件
hydrogen bromide T=0°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 50, # 10 p. 1621 - 1626
反应条件
tin(ll) chloride in ethanol T=90°C; 15 h;
参考文献
Takeuchi, Ryo; Sugiura, Masaharu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 9 p. 1031 - 1038
反应条件
toluene-4-sulfonic acid in methanol; water
参考文献
Bulletin de la Societe Chimique de France, , vol. <II>, p. 299 - 303
反应条件
ethylmagnesium bromide in tetrahydrofuran 9 h; Heating;
参考文献
Novokshonov; Medvedeva; Demina; Sherstyannikova; Voronkov
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 12 p. 1770 - 1773
反应条件
tin; aluminium 1.) diglyme-H2O, RT; 2.) diglyme-H2O, RT; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chemistry Letters, , p. 1939 - 1942
反应条件
1H-imidazole in N,N-dimethyl-formamide T=20°C;
参考文献
GLYCOMIMETICS, INC.; ERNST, Beat; WECKERLE, Celine, E.; EGGER, Jonas, K.
Patent: WO2012/37034 A1, 2012 ;
Location in patent: Page/Page column 43 ;
