4-(3-溴丙基氧基)苯甲醛合成路线 （共 11 条）
反应条件
potassium carbonate in acetonitrile T=40°C; 4 h;
参考文献
Pan, Long-Fei; Wang, Xiao-Bing; Xie, Sai-Sai; Li, Su-Yi; Kong, Ling-Yi
MedChemComm, 2014 , vol. 5, # 5 p. 609 - 616
反应条件
potassium carbonate in acetonitrile T=20 - 60°C; 3 - 4 h; Industry scale;
参考文献
DESTINY PHARMA LIMITED; SOLVIAS AG
Patent: WO2007/74340 A1, 2007 ;
Location in patent: Page/Page column title page; 18-20; Sheet 1/2 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 20°C; Mitsunobu reaction; 4 h;
参考文献
Le Sann, Christine; Baron, Anne; Mann, John; Van Den Berg, Hendrik; Gunaratnam, Mekala; Neidle, Stephen
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 7 p. 1305 - 1312
反应条件
potassium carbonate in acetone 20 h; Heating;
参考文献
Levoin, Nicolas; Labeeuw, Olivier; Calmels, Thierry; Poupardin-Olivier, Olivia; Berrebi-Bertrand, Isabelle; Lecomte, Jeanne-Marie; Schwartz, Jean-Charles; Capet, Marc
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5378 - 5383
反应条件
in methanol T=20°C; 48 h;
参考文献
Moutevelis-Minakakis, Panagiota; Papavassilopoulou, Eleni; Mavromoustakos, Thomas
Molecules, 2013 , vol. 18, # 1 p. 50 - 73
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene 1 h; Heating;
参考文献
Tetrahedron Letters, , vol. 34, # 14 p. 2343 - 2346
参考文献
Chaudhuri, Padmaparna; Majumder, Hemanta K.; Bhattacharya, Santanu
Journal of Medicinal Chemistry, 2007 , vol. 50, # 10 p. 2536 - 2540
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 6 h;
参考文献
Manohar, Sunny; Khan, Shabana I.; Kandi, Shamseer Kulangara; Raj, Kranthi; Sun, Guojing; Yang, Xiaochuan; Calderon Molina, Angie D.; Ni, Nanting; Wang, Binghe; Rawat, Diwan S.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 112 - 116
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
1 h; Heating;
参考文献
Lee, Eun; Lee, Chulbom; Tae, Jin Sung; Whang, Ho Sung; Li, Kap Sok
Tetrahedron Letters, 1993 , vol. 34, # 14 p. 2343 - 2346
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
T=110°C; 3 h;
参考文献
Manohar, Sunny; Khan, Shabana I.; Kandi, Shamseer Kulangara; Raj, Kranthi; Sun, Guojing; Yang, Xiaochuan; Calderon Molina, Angie D.; Ni, Nanting; Wang, Binghe; Rawat, Diwan S.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 112 - 116
