7-亚甲基双环[3.3.1]壬-3-酮合成路线 （共 44 条）
反应条件
potassium hydroxide in 1,4-dioxane T=140°C; 14 h;
参考文献
Mink, Larry; Rettig, Michael F.; Wing, Richard M.
Journal of the American Chemical Society, 1991 , vol. 113, # 6 p. 2065 - 2071
反应条件
pyridine; p-toluenesulfonyl chloride in benzene T=70°C; 12 h;
参考文献
Muraoka; Wang; Okumura; Nishiura; Tanabe; Momose
Synthetic Communications, 1996 , vol. 26, # 8 p. 1555 - 1562
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 111, # 20 p. 8032 - 8034
反应条件
3,3-dimethyldioxirane in dichloromethane; acetone 20 h;
参考文献
Journal of the American Chemical Society, , vol. 123, # 45 p. 11248 - 11252
反应条件
potassium hydroxide in dimethyl sulfoxide 16 h; Heating;
参考文献
Adcock, William; Kok, Gaik B.
Journal of Organic Chemistry, 1987 , vol. 52, # 3 p. 356 - 364
反应条件
1: 87 percent / Br2, AlBr3, BBr3 / 1.5 h / 85 °C 2: 83 percent / 1 M NaOH / dioxane / 16 h / 185 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 113, # 6 p. 2177 - 2194
反应条件
1: 94 percent / KOH / dimethylsulfoxide / 0.5 h / 100 °C 2: hydriodic acid / hexane; benzene / 36 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 3 p. 356 - 364
反应条件
hydrogen iodide in hexane; benzene 36 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 52, # 3 p. 356 - 364
反应条件
sodium hydroxide T=180°C;
参考文献
Tetrahedron, , vol. 27, p. 4317 - 4322
反应条件
nitric acid 60 h; Ambient temperature;
参考文献
Pharmaceutical Chemistry Journal, , vol. 26, # 7 p. 616 - 618
Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 7-8 p. 58 - 59
