4-氟-2-羟基苯甲酸乙酯合成路线 （共 6 条）
反应条件
sulfuric acid Heating;
参考文献
Kissei Pharmaceutical Co., Ltd.
Patent: EP2133332 A1, 2009 ;
Location in patent: Page/Page column 21 ;
EP 2133332 A1
反应条件
sodium acetate in N-methyl-acetamide
参考文献
Kabi Pharmacia AB
Patent: US5302718 A1, 1994 ;
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate); trifluoroacetic acid; trifluoroacetic anhydride T=110°C; 14 h;
参考文献
Yang, Yiqing; Lin, Yun; Rao, Yu
Organic Letters, 2012 , vol. 14, # 11 p. 2874 - 2877
反应条件
[Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate); trifluoroacetic acid; trifluoroacetic anhydride T=80°C; 3 h;
参考文献
Yang, Yiqing; Lin, Yun; Rao, Yu
Organic Letters, 2012 , vol. 14, # 11 p. 2874 - 2877
反应条件
1: (i) HF, H3BO3, (ii) NaNO2, (iii) (thermolysis) 2: H2SO4 / Heating View Scheme
参考文献
Ostaszyuski,A. et al.
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1960 , vol. 8, p. 591 - 597
反应条件
hydroxylamine hydrochloride; sodium ethanolate in ethanol
参考文献
Ostaszyuski,A. et al.
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1960 , vol. 8, p. 591 - 597
