(R)-(+)-1-苯基-1-丙醇合成路线 (共 130 条)
反应条件
diethylzinc; [2-((S)-4-tBu-4,5-H2-oxazol-2-yl)-1-(C(OH)Ph2)]-ferrocene in n-heptane; toluene T=10°C; 12 h; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 346, # 7 p. 867 - 872
反应条件
(R)-5-nitro-2-phenyl-2,3-dihydroimidazo[1,2-a]pyridine in chloroform-d1 T=20°C; 1 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2005/256150 A1, ;
Page/Page column 15 ;
反应条件
CH2CH2O(C10H5O)4H2P2N2(CH3)4; [{RuCl2(cymene)}2]; potassium carbonate in water; toluene T=60°C; 16 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Molecules, , vol. 16, # 6 p. 5020 - 5034
反应条件
benzo[1,3,2]dioxaborole; chiral boron-bis(oxazoline) derivative in dichloromethane T=25°C; 48 h;
参考文献
European Journal of Organic Chemistry, , # 20 p. 4596 - 4608
反应条件
polyoxyethylene (10) cetyl ether; n-octyl beta-D-glucopyranoside; subtilisin Carlsberg; sodium carbonate in tetrahydrofuran T=20°C; 17 h; Title compound not separated from byproducts;
参考文献
Chemistry - A European Journal, , vol. 12, # 1 p. 225 - 232
反应条件
benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 47 p. 8314 - 8317
反应条件
lipase B from Candida antarctica in cyclohexane T=50°C; 0.75 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Journal of Catalysis, , vol. 288, p. 24 - 32
反应条件
1: isopropyl alcohol With [Ru(1,5-cyclooctadiene)Cl2]x; (8R,9R)-9-amino-(9-deoxy)epiquinine T=20°C; 0.5 h; Inert atmosphere; 2: With potassium hydroxide 0.5 h; Inert atmosphere; 3: 1-phenyl-propan-1-one T=0°C; 96 h; Inert atmosphere; enantioselective reaction;
参考文献
Journal of Chemical Research, , vol. 37, # 12 p. 761 - 763
反应条件
(-)-erythro-PMPM in hexane T=0°C;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 6 p. 467 - 468
反应条件
novozyme 435 in toluene T=60°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 18, # 13 p. 1618 - 1624