2-(3-羟基-丙基)-苯酚合成路线 （共 34 条）
反应条件
1: 85 percent / 9-BBN; H2O2; aq. NaOH / tetrahydrofuran / 0 - 15 °C
2: TBAF / tetrahydrofuran / 1 h / 0 - 20 °C
View Scheme
参考文献
Camacho; Nakamura; Saito; Yamamoto
Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 270 - 275
反应条件
1: 95 percent / imidazole / dimethylformamide / 50 °C
2: 85 percent / 9-BBN; H2O2; aq. NaOH / tetrahydrofuran / 0 - 15 °C
3: TBAF / tetrahydrofuran / 1 h / 0 - 20 °C
View Scheme
参考文献
Camacho; Nakamura; Saito; Yamamoto
Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 270 - 275
反应条件
1: acetonitrile; H2O / 50 °C / rate constants (kOH) for lactonization (buffered solution pH 10.0); other temp.: 70, 90 deg C
2: 91 percent / lithium aluminum hydride / tetrahydrofuran
View Scheme
参考文献
Amsberry, Kent L.; Borchardt, Ronald T.
Journal of Organic Chemistry, 1990 , vol. 55, # 23 p. 5867 - 5877
反应条件
aluminium trichloride; sodium iodide in acetonitrile
6 h; Ambient temperature;
参考文献
Node, Manabu; Ohta, Keiichiro; Kajimoto, Tetsuya; Nishide, Kiyoharu; Fujita, Eiichi; Fuji, Kaoru
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 4178 - 4180
反应条件
1: 90 percent / methanol / 0.5 h
2: 80 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
View Scheme
参考文献
Yadav, Veejendra K; Ganesh Babu; Mittal, Manish
Tetrahedron, 2001 , vol. 57, # 32 p. 7047 - 7051
反应条件
T=250°C; P=73550.8 - 147102 Torr; Hydrogenation;
参考文献
de Benneville; Connor
Journal of the American Chemical Society, 1940 , vol. 62, p. 283,284
反应条件
lithium aluminium tetrahydride; cerium(III) chloride in tetrahydrofuran
0.166667 h; Ambient temperatureOther catalyst, without catalyst; Product distribution;
参考文献
Fukuzawa, Shin-ichi; Fujinami, Tatsuo; Yamauchi, Shoji; Sakai, Shizuyoshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1929 - 1932
反应条件
sodium tetrahydroborate; sodium carbonate in water
3 h; Ambient temperaturewith or without β-cyclodextrin; variation of solvent, temperature and substrate/reducing agent ratio; Product distribution;
参考文献
Pitchumani, Kasi; Velusamy, Ponnusamy; Srinivasan, Chockalingam
Tetrahedron, 1994 , vol. 50, # 45 p. 12979 - 12988
参考文献
Karrer; Banerjea
Helvetica Chimica Acta, 1949 , vol. 32, p. 1692
反应条件
1: aqueous NaOH
2: pyridine; SOCl2
3: potassium cyanide; ethanol / Erhitzen des Reaktionsprodukts mit methanol. KOH
View Scheme
参考文献
Lockett; Short
Journal of the Chemical Society, 1939 , p. 787,789
