1-吡咯里嗪-2,4-二硝基苯合成路线 （共 28 条）
反应条件
sodium hydroxide in 1,4-dioxane; water T=25°C; ionic strength μ= 1 M (NaCl), in the presence or absenece of pyrrolidine, variation of concentrations of base and amine; Rate constantMechanism;
参考文献
Gierczyk; Leska; Nowak-Wydra; Schroeder; Wojciechowski; Bartl; Brzezinski
Journal of Molecular Structure, 2000 , vol. 524, # 1-3 p. 217 - 225
反应条件
in dimethyl sulfoxide T=50°C; 2 h;
参考文献
Sekiguchi, Shizen; Ishikura, Hiromi; Hirosawa, Yukitoshi; Ono, Nobuyuki
Tetrahedron, 1990 , vol. 46, # 16 p. 5567 - 5578
反应条件
in dimethyl sulfoxide
参考文献
Sekiguchi, Shizen; Ishikura, Hiromi; Hirosawa, Yukitoshi; Ono, Nobuyuki
Tetrahedron, 1990 , vol. 46, # 16 p. 5567 - 5578
反应条件
sodium hydroxide in 1,4-dioxane; water
T=30°C; ionic strength O.1M (NaCl); reaction in the absence of NaOH, NaOH concentration dependence; aminodephenoxylation with pyrrolidine and piperidine and hydroxydephenylation with NaOH of substituted diphenyl ethers; Rate constantMechanism;
参考文献
Bunnett, Joseph F.; Cartano, Artemio V.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4861 - 4865
反应条件
in 1,4-dioxane; water
T=30°C; ionic strength O.1M (NaCl); reaction with pyrrolidine in the presence and absence of NaOH, NaOH concentration dependence; aminodephenoxylation with pyrrolidine and piperidine and hydroxydephenylation with NaOH of substituted diphenyl ethers; Rate constantMechanism;
参考文献
Bunnett, Joseph F.; Cartano, Artemio V.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4861 - 4865
反应条件
288 h; Ambient temperature;
参考文献
Buchholz, Berthold; Onistschenko, Andreas; Stamm, Helmut
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1986 , vol. 41, # 10 p. 1311 - 1314
反应条件
in dimethyl sulfoxide
T=25°C; Rate constantEquilibrium constant;
参考文献
Chamberlin, Rachel A.; Crampton, Michael R.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 10 p. 1831 - 1838
反应条件
silver nitrate in chloroform-d1
T=20°C; Thermodynamic data; Reagent/catalyst;
参考文献
Verbeeck, Stefan; Herrebout, Wouter A.; Gulevskaya, Anna V.; Van Der Veken, Benjamin J.; Maes, Bert U. W.
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5126 - 5133
反应条件
in acetonitrile
T=25°C; Kinetics; Further Variations:amine concentration;
参考文献
Crampton, Michael R.; Emokpae, Thomas A.; Isanbor, Chukwuemeka
European Journal of Organic Chemistry, 2007 , # 8 p. 1378 - 1383
反应条件
in acetonitrile
T=25°C; also with other secondary amines; MechanismRate constant;
参考文献
Cho, Bong Rae; Je, Jong Tae
Journal of Organic Chemistry, 1993 , vol. 58, # 23 p. 6190 - 6193
