2-甲基-4-苯基-1H-咪唑合成路线 （共 10 条）
反应条件
ammonium acetate; acetic acid in xylene 6 h; Reflux;
参考文献
MASSACHUSETTS INSTITUTE OF TECHNOLOGY; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; GENZYME CORPORATION
Patent: WO2009/137081 A2, 2009 ;
Location in patent: Page/Page column 49-51 ;
WO 2009/137081 A2
反应条件
potassium hydroxide in methanol 14 h; Ambient temperature;
参考文献
Watanabe, T.; Nishiyama, J.; Hirate, R.; Uehara, K.; Inoue, M.; et al.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1277 - 1281
反应条件
T=100°C; Bredereck Imidazole Synthesis; 0.25 h;
参考文献
Journal of Chemical Research, , vol. 38, # 4 p. 208 - 210
反应条件
dihydrogen peroxide; acetic acid T=70°C; 6 h;
参考文献
Heterocycles, , vol. 16, # 4 p. 573 - 576
反应条件
1: acetonitrile / 0.75 h / Heating 2: acetonitrile; CHCl3 / 3.5 h / Heating View Scheme
参考文献
Synthesis, , # 14 p. 2075 - 2077
反应条件
in chloroform; acetonitrile 3.5 h; Heating;
参考文献
Synthesis, , # 14 p. 2075 - 2077
反应条件
1: water 2: copper (II)-acetate; aqueous NH3 View Scheme
参考文献
Chemische Berichte, , vol. 68, p. 1953,1956
反应条件
ammonium hydroxide; copper diacetate
参考文献
Chemische Berichte, , vol. 68, p. 1953,1956
反应条件
n-butyllithium in tetrahydrofuran; hexane 1) -70 -> -80 deg C, 1 h, 2) r.t., 12-16 h;
参考文献
Chemische Berichte, , vol. 126, # 1 p. 129 - 132
参考文献
Chemische Berichte, , vol. 86, p. 96,107
