1-甲氧基-1,2-丙二烯合成路线 （共 58 条）
反应条件
potassium tert-butylate 1 h; Heating / reflux;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2004/69256 A1, 2004 ;
Location in patent: Page/Page column 34 ;
WO 2004/069256 A1
反应条件
potassium tert-butylate 3 h; Heating / reflux;
参考文献
RECORDATI IRELAND LIMITED; RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A.
Patent: WO2007/25780 A2, 2007 ;
Location in patent: Page/Page column 118 ;
WO 2007/025780 A2
反应条件
potassium tert-butylate 3 h; Heating;
参考文献
Chengebroyen, Jaganaiden; Linke, Myriam; Robitzer, Mike; Sirlin, Claude; Pfeffer, Michel
Journal of Organometallic Chemistry, 2003 , vol. 687, # 2 p. 313 - 321
参考文献
Bayer Aktiengesellschaft
Patent: US5246966 A1, 1993 ;
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; samarium diiodide; tert-butyl alcohol in tetrahydrofuran T=20°C; 16 h; Title compound not separated from byproducts;
参考文献
Hoelemann, Alexandra; Reissig, Hans-Ulrich
Organic Letters, 2003 , vol. 5, # 9 p. 1463 - 1466
反应条件
(i) nBuLi, Et2O, (ii) /BRN= 1730824/; Multistep reaction;
参考文献
Hoff,S. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1968 , vol. 87, p. 1179 - 1184
反应条件
(i) nBuLi, Et2O, (ii) /BRN= 385735/; Multistep reaction;
参考文献
Yoneda, Eiji; Kaneko, Takayuki; Zhang, Shi-Wei; Onitsuka, Kiyotaka; Takahashi, Shigetoshi
Organic Letters, 2000 , vol. 2, # 4 p. 441 - 443
反应条件
hydroquinone T=90°C; 72 h; chemoselectivity, stereochemistry of cycloaddition in dependence on temperature, time, concentration of allene; MechanismProduct distribution;
参考文献
Jendralla, Heiner; Laumen, Kurt
Chemische Berichte, 1983 , vol. 116, # 6 p. 2136 - 2164
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran (Ar), stirred for 48 h at room temp.; total adduct yield 75percent; removed solvent; GLC, NMR;
参考文献
Mitchell, Terence N.; Schneider, Ulrich
Journal of Organometallic Chemistry, 1991 , vol. 405, # 2 p. 195 - 199
反应条件
fluorine; NAF T=-100 - -10°C; 12 h;
参考文献
Arimura, Takashi; Shibakami, Motonari; Tamura, Masanori; Kurosawa, Shigeru; Sekiya, Akira
Journal of Chemical Research, Miniprint, 1994 , # 3 p. 588 - 598
