N,N-二异丙基亚膦酸二甲酯酰胺合成路线 （共 12 条）
反应条件
in tetrahydrofuran T=-35 - 20°C;
参考文献
Dias; Mornet; Kotoujansky
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 1 p. 73 - 78
反应条件
triethylamine in diethyl ether T=20°C; Substitution;
参考文献
Shukla, Deepak; Lu, Cuong; Schepp, Norman P.; Bentrude, Wesley G.; Johnston, Linda J.
Journal of Organic Chemistry, 2000 , vol. 65, # 19 p. 6167 - 6172
反应条件
N-ethyl-N,N-diisopropylamine in hexane 2 h; Ambient temperature;
参考文献
Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 7 p. 1621 - 1628
反应条件
in acetonitrile 1 h;
参考文献
McBride, Lincoln J.; Kierzek, Ryszard; Beaucage, Serge L.; Caruthers, Marvin H.
Journal of the American Chemical Society, 1986 , vol. 108, # 8 p. 2040 - 2048
反应条件
1: 82 percent / PCl3 / hexane / 1 h / Ambient temperature 2: 49 percent / iPr2NEt / hexane / 2 h / Ambient temperature View Scheme
参考文献
Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 7 p. 1621 - 1628
反应条件
tris(2,4,6-tribromo-phenoxy)dichlorophosphorane; N-ethyl-N,N-diisopropylamine 1) pyridine, 2) 5 min; Yield given. Multistep reaction;
参考文献
Wada; Ishikawa; Hata
Tetrahedron Letters, 1990 , vol. 31, # 44 p. 6363 - 6366
反应条件
pyridine hydrochloride in pyridine; water 0.0833333 h;
参考文献
Wada; Ishikawa; Hata
Tetrahedron Letters, 1990 , vol. 31, # 44 p. 6363 - 6366
反应条件
in chloroform Ambient temperature;
参考文献
Dias; Mornet; Kotoujansky
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 1 p. 73 - 78
反应条件
in acetonitrile stoichiometry and equilibrium; partial reactions; reaction with tert-butyl alcohol in the presence and absence of tetrazole; kinetic and mechanism of tetrazole-catalyzed phosphoramidite alcoholysis; 31P NMR study; Product distribution;
参考文献
Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 7 p. 1621 - 1628
反应条件
1H-tetrazole in acetonitrile
T=20°C;
参考文献
Boehrsch, Verena; Serwa, Remigiusz; Majkut, Paul; Krause, Eberhard; Hackenberger, Christian P. R.
Chemical Communications, 2010 , vol. 46, # 18 p. 3176 - 3178
