2-氨基-1-环己烯-1-甲酸乙酯合成路线 （共 15 条）
反应条件
ammonium carbamate in methanol T=20°C;
参考文献
SYNGENTA PARTICIPATIONS AG; POULIOT, Martin; QUARANTA, Laura; TRAH, Stephan
Patent: WO2013/26900 A1, 2013 ;
Location in patent: Page/Page column 60 ;
反应条件
1: With methanesulfonic acid; zinc in tetrahydrofuran Inert atmosphereReflux; 2: With lithium hexamethyldisilazane in tetrahydrofuran T=0 - 20°C; 5 h; Inert atmosphere;
参考文献
Synthesis (Germany), , vol. 44, # 12 art. no. SS-2012-C0191-ST, p. 1809 - 1817
反应条件
methanesulfonic acid; zinc in tetrahydrofuran Blaise reaction; 7 h; RefluxInert atmosphere; chemoselective reaction;
参考文献
Kim, Juhyun; Chun, Yusung; Shin, Hyunik; Lee, Sang-Gi
Synthesis (Germany), 2012 , vol. 44, # 12 art. no. SS-2012-C0191-ST, p. 1809 - 1817
反应条件
methanesulfonic acid; zinc in tetrahydrofuran Blaise reaction; 5 h; RefluxInert atmosphere; chemoselective reaction;
参考文献
Kim, Ju Hyun; Shin, Hyunik; Lee, Sang-Gi
Journal of Organic Chemistry, 2012 , vol. 77, # 3 p. 1560 - 1565
反应条件
T=140 - 150°C; im geschlossenen Rohr;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 317, p. 104
参考文献
Justus Liebigs Annalen der Chemie, , vol. 317, p. 104
反应条件
1: sodium ethylate; ethanol 2: water; hydrochloric acid 3: phosphoryl chloride / 180 °C 4: Raney nickel; sodium methylate; methanol / Hydrogenation 5: palladium/charcoal / 300 °C View Scheme
参考文献
Prelog; Szpilfogel
Helvetica Chimica Acta, 1945 , vol. 28, p. 1684,1690
反应条件
1: platinum; acetic acid / Hydrogenation 2: aqueous hydrochloric acid View Scheme
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
反应条件
1: platinum; acetic acid / Hydrogenation 2: aqueous hydrochloric acid View Scheme
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
反应条件
1: platinum; acetic acid / Hydrogenation 2: aqueous hydrochloric acid View Scheme
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
