1-(氯甲基)-4-硝基苯合成路线 (共 349 条)
反应条件
in N,N-dimethyl-formamide
T=-16°C; Alkylation; 35 h;
参考文献
Vanelle, Patrice; Gellis, Armand; Kaafarani, Mustapha; Maldonado, Jose; Crozet, Michel P.
Tetrahedron Letters, 1999 , vol. 40, # 23 p. 4343 - 4346
反应条件
N,N-di-tert-butylnitroxide in acetonitrile
T=20°C; Substitution; 1 h;
参考文献
Costentin, Cyrille; Hapiot, Philippe; Medebielle, Maurice; Saveant, Jean-Michel
Journal of the American Chemical Society, 2000 , vol. 122, # 23 p. 5623 - 5635
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
Hass-Bender/Henry reaction;
参考文献
Klein, Thomas A.; Schkeryantz, Jeffrey M.
Tetrahedron Letters, 2005 , vol. 46, # 27 p. 4535 - 4538
反应条件
1: Na / ethanol
2: aq. H2O2 / acetic acid
3: LiOEt / dimethylformamide / Irradiation
View Scheme
参考文献
Russell,G.A.; Pecoraro,J.M.
Journal of the American Chemical Society, 1979 , vol. 101, p. 3331 - 3334
反应条件
in water
T=100°C; Alkylation; 0.0666667 h; Irradiation;
参考文献
Vanelle, Patrice; Gellis, Armand; Kaafarani, Mustapha; Maldonado, Jose; Crozet, Michel P.
Tetrahedron Letters, 1999 , vol. 40, # 23 p. 4343 - 4346
参考文献
Huber, Didier; Andermann, Guy; Lecrerc, Gerard
Tetrahedron Letters, 1988 , vol. 29, # 6 p. 635 - 638
参考文献
Hass; Berry; Bender
Journal of the American Chemical Society, 1949 , vol. 71, p. 2290
反应条件
in methanol; water
48 h; Ambient temperature;
参考文献
Hilhorst, Ellen; Iskander, Atef S.; Chen, Tjoe B. R. A.; Pandit, Upendra K.
Tetrahedron, 1994 , vol. 50, # 29 p. 8863 - 8870
反应条件
sulfuric acid; sodium in ethanol; dichloromethane; water
参考文献
Aventis Pharma S.A.
Patent: US6352839 B1, 2002 ;
反应条件
BZTMETB; sulfur in methanol
T=20°C; 0.0833333 h;
参考文献
Tajbakhsh, Mahmood; Lakouraj, Moslem M.; Mahalli, Majid S.
Monatshefte fur Chemie, 2008 , vol. 139, # 12 p. 1453 - 1456