盐酸乙脒

盐酸乙脒

Acetamidine Hydrochloride

124-42-5

C2H7ClN2

94.54340

49.87000

1.54430

94.02980

1.458

无色至白色固体

26.1ºC

62.8ºC at 760mmHg

165-170 °C(lit.)

1 g/mL

176mmHg at 25°C

Stable at room temperature in closed containers under normal storage and handling conditions.

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

3

29252000

S26-S37/39

Xi

R36/38

2933990090

2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

<p>生产方法简述:由乙腈、盐酸和甲醇经加成、氨化而得。使甲醇在湍球塔内循环,压力小于26.6kPa,冷却下通入干燥的氯化氢,制成浓度为45%的氯化氢甲醇溶液。然后投入反应罐,搅拌冷却至10-5℃,滴加乙腈,并于15-20℃保温6h,得亚胺基甲乙醚盐酸盐。放入预先配制好的13%氨甲醇溶液中,在0-40℃氨解,保持pH值7-8,搅拌2-3h,降温至30℃以下,离心分离滤出氯化铵。滤液回收甲醇,冷却过滤得成品。重量投料比:乙腈:氯化氢甲醇溶液(45%):氨:甲醇=1:3:1.05:4.3。收率82%-85%。</p>

<p>用于合成咪唑类、嘧啶类、三嗪类抗菌素,还用于合成维生素B1。</p>