3-乙氧基-2-丁炔羧酸乙酯合成路线 （共 46 条）
反应条件
1: ethyl acetoacetate With sulfuric acid in ethanol T=50°C; Inert atmosphere; 2: orthoformic acid triethyl ester T=50°C; 16 h;
参考文献
PFIZER LIMITED; BELL, Andrew Simon; GARDNER, Iain Brian; PRYDE, David Cameron; WAKENHUT, Florian Michel; GIBSON, Karl Richard
Patent: WO2012/66442 A1, 2012 ;
Location in patent: Page/Page column 23 ;
反应条件
toluene-4-sulfonic acid in ethanol T=65°C; Alkylation;
参考文献
Carbonnel, Sylvie; Fayet, Catherine; Gelas, Jacques
Carbohydrate Research, 1999 , vol. 319, # 1-4 p. 63 - 73
反应条件
diethyl ether T=25°C;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 254,259
反应条件
diethyl ether T=25°C;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 254,259
反应条件
diethyl ether T=25°C;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 254,259
反应条件
diethyl ether T=25°C;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 254,259
反应条件
diethyl ether T=25°C;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 254,259
反应条件
potassium carbonate in dichloromethane 17 h; Ambient temperature;
参考文献
Synthesis, , # 11 p. 926 - 929
反应条件
boron trifluoride diethyl etherate in diethyl ether
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 85, p. 929 - 951
反应条件
in ethanol T=0°C; 24 h;
参考文献
Journal of the Chemical Society, , p. 2349 - 2366
