2-(2-氯苯基)-4,4-二甲基-4,5-二氢-1,3-恶唑合成路线 （共 11 条）
反应条件
in diethyl ether 18 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
in diethyl ether 1 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
1: in chloroform
T=80°C; P=206.859 - 517.148 Torr; 0.166667 h; microwave irradiation;
2: With thionyl chloride in chloroform
T=80°C; 0.0333333 h; microwave irradiation;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
1: salicylic acid With pyridine; 2,4,6-trichloro-1,3,5-triazine in dichloromethane
T=0°C; 0.25 h;
2: 2-amino-2-methyl-propan-1-ol With indium in dichloromethane
T=20°C; 30 h;
参考文献
Kangani, Cyrous O.; Day, Billy W.
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5332 - 5335
反应条件
pyridine; p-toluenesulfonyl chloride
参考文献
Boyd,R.N.; Rittner,R.C.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2032 - 2034
反应条件
1.1: SOCl2 / 0.5 h / 25 °C
1.2: 2 h / 25 °C
2.1: CHCl3 / 0.17 h / 80 °C / 206.86 - 517.15 Torr / microwave irradiation
2.2: 98 percent / SOCl2 / CHCl3 / 0.03 h / 80 °C / microwave irradiation
View Scheme
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
in diethyl ether
1 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
in diethyl ether
18 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
反应条件
manganese (II) chloride in tetrahydrofuran
T=20°C; Substitution; Cross-coupling reaction; 24 h;
参考文献
Cahiez, Gerard; Lepifre, Franck; Ramiandrasoa, Parfait
Synthesis, 1999 , # 12 p. 2138 - 2144
反应条件
in diethyl ether
1 h; Heating;
参考文献
Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T.
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
