4-碘-2-三氟甲基乙酰胺合成路线 （共 8 条）
反应条件
copper diacetate; palladium diacetate; 2,2,2-trimethylacetic acid in 1,2-dichloro-ethane T=110°C; 24 h; Inert atmosphereSchlenk techniqueSealed tubeGreen chemistry;
参考文献
Zhang, Li-Sheng; Chen, Kang; Chen, Guihua; Li, Bi-Jie; Luo, Shuang; Guo, Qing-Yun; Wei, Jiang-Bo; Shi, Zhang-Jie
Organic Letters, 2013 , vol. 15, # 1 p. 10 - 13
反应条件
in toluene 5 h; Heating;
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
反应条件
1: I2, CaCO3 / methanol; H2O / 24 h / 45 °C 2: 89 percent / toluene / 5 h / Heating View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 34, # 11 A p. 1612 - 1624
反应条件
1: 71 percent / hexamethylphosphoric acid triamide / 3 h / 150 °C 2: 78 percent / 50percent NaOH / H2O; ethanol / 5 h / Heating View Scheme
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
反应条件
1: 71 percent / hexamethylphosphoric acid triamide / 3 h / 150 °C 2: 78 percent / 50percent NaOH / H2O; ethanol / 5 h / Heating 3: 56 percent / SO2Cl2 / CHCl3 / 8 h / Heating View Scheme
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
反应条件
1: 71 percent / hexamethylphosphoric acid triamide / 3 h / 150 °C 2: 78 percent / 50percent NaOH / H2O; ethanol / 5 h / Heating 3: 56 percent / SO2Cl2 / CHCl3 / 8 h / Heating 4: SOCl2 / 2 h / Heating View Scheme
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=150°C; 3 h;
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
反应条件
1: 71 percent / hexamethylphosphoric acid triamide / 3 h / 150 °C
2: 78 percent / 50percent NaOH / H2O; ethanol / 5 h / Heating
3: 63 percent / Br2 / acetic acid
View Scheme
参考文献
Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624
