N-alpha-苯甲酰基-L-精氨酸乙酯盐酸盐合成路线 (共 41 条)
反应条件
ethylenediaminetetraacetic acid; water; mercaptoacetic acid in dimethyl sulfoxide papain-cat. hydrolysis (spec. activity); phosphate buffer (pH=8.5);
参考文献
Bowen, Sean; Hilty, Christian
Angewandte Chemie - International Edition, 2008 , vol. 47, # 28 p. 5235 - 5237
反应条件
subtilisin BPN' in methanol; water kcat and Km; other cosolvents; pH 8.0; Rate constant;
参考文献
Wong; Chen; Hennen; Bibbs; Wang; L iu; Pantoliano; Whitlow; Bryan
Journal of the American Chemical Society, 1990 , vol. 112, # 3 p. 945 - 953
反应条件
hydrogenchloride; borate buffer; sodium chloride; calcium chloride; trypsin in water T=30°C; var. of substrate, amino acid amide, conc.; Product distribution;
参考文献
Salchert; Ullmann; Jakubke
Pharmazie, 1996 , vol. 51, # 10 p. 710 - 714
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679
反应条件
clostripain; sodium chloride; calcium chloride in acetate buffer T=25°C; Hydrolysis; acylation; pH=10.0; Enzymatic reaction; Product distribution;
参考文献
Guenther, Robert; Stein, Anja; Bordusa, Frank
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1672 - 1679