N-苄基-4-苯氨基哌啶-4-氰基合成路线 （共 22 条）
反应条件
in water; acetic acid T=25°C; 24 h;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 90, # 7 p. 749 - 756
反应条件
1: 1-Phenylmethyl-piperidin-4-one; aniline With acetic acid T=0°C; Strecker reaction; 2: potassium cyanide in water Strecker reaction; 18.5 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 57, # 12 p. 1421 - 1424
反应条件
1: in acetic acid T=0 - 40°C; 1.16667 h; 2: With ammonia in water T=0°C; pH=10;
参考文献
EP1559428 A1, ;
Page/Page column 33 ;
EP 1559428 A1
反应条件
potassium cyanide; acetic acid; aniline in isopropyl alcohol
参考文献
US8742111 B1, ;
Page/Page column ;
反应条件
acetic acid in water Addition; 28 h;
参考文献
Tetrahedron, , vol. 55, # 24 p. 7625 - 7644
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene Cyclization; reduction; nitrile transfer; 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 64, # 15 p. 5504 - 5510
反应条件
1: With 2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene Cyclization; reduction; nitrile transfer; 16 h; Heating; 2: With ammonium hydroxide in toluene Hydrolysis; 0.666667 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 15 p. 5504 - 5510
反应条件
1: 69 percent / acetic acid / 65 h / 20 °C 2: AIBN; tributyltin hydride / toluene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 15 p. 5504 - 5510
反应条件
1: 69 percent / acetic acid / 65 h / 20 °C 2: AIBN; tributyltin hydride / toluene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 15 p. 5504 - 5510
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 55, # 13 p. 4207 - 4209
