(S)-4-叔丁氧羰基氨基-5-叔丁基二甲基硅氧基戊酸甲酯合成路线 （共 10 条）
反应条件
sodium hydride in diethyl ether 16 h;
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
toluene-4-sulfonic acid in methanol T=20°C; 3 h;
参考文献
Wierzejska, Jolanta; Motogoe, Shin-Ichi; Makino, Yuto; Sengoku, Tetsuya; Takahashi, Masaki; Yoda, Hidemi
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1831 - 1838,8
反应条件
sodium methylate in methanol
T=20°C; 0.166667 h;
参考文献
Wierzejska, Jolanta; Motogoe, Shin-Ichi; Makino, Yuto; Sengoku, Tetsuya; Takahashi, Masaki; Yoda, Hidemi
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1831 - 1838,8
反应条件
1H-imidazole in N,N-dimethyl-formamide
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
1: 1.) NaHCO3 / 1.) H2O, 2.) 1,4-dioxane, 16 h, room temperature
2: DCC / ethyl acetate / 1.) 0 deg C, 2.) 3 h, room temperature
3: NaBH4 / ethanol; tetrahydrofuran / 0.25 h / 0 °C
4: 92 percent / imidazole / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
1: 1.) NaHCO3 / 1.) H2O, 2.) 1,4-dioxane, 16 h, room temperature
2: DCC / ethyl acetate / 1.) 0 deg C, 2.) 3 h, room temperature
3: NaBH4 / ethanol; tetrahydrofuran / 0.25 h / 0 °C
4: 92 percent / imidazole / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
1: DCC / ethyl acetate / 1.) 0 deg C, 2.) 3 h, room temperature
2: NaBH4 / ethanol; tetrahydrofuran / 0.25 h / 0 °C
3: 92 percent / imidazole / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
1: NaBH4 / ethanol; tetrahydrofuran / 0.25 h / 0 °C
2: 92 percent / imidazole / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Shimamoto, Keiko; Ishida, Michiko; Shinozaki, Haruhikio; Ohfune, Yasufumi
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4167 - 4176
反应条件
1: 86 percent / Et3N / dioxane; H2O
View Scheme
参考文献
Burkhart; Holbert; Metcalf
Tetrahedron Letters, 1984 , vol. 25, # 46 p. 5267 - 5270
参考文献
Burkhart; Holbert; Metcalf
Tetrahedron Letters, 1984 , vol. 25, # 46 p. 5267 - 5270
