(Z)-1,4-二苯基-2-丁烯-1,4-二酮合成路线 （共 65 条）
反应条件
in dichloromethane
24 h; Ambient temperature; Yields of byproduct given;
参考文献
Chien, Chun-Sheng; Kawasaki, Tomomi; Sakamoto, Masanori; Tamura, Yasumitsu; Kita, Yasuyuki
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2743 - 2749
反应条件
1.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / 0.17 h / 20 °C
1.2: 8 h / 50 °C
2.1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
3.1: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 10 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
2: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 10 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
1.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / 0.17 h / 20 °C
1.2: 8 h / 50 °C
2.1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
3.1: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 10 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
potassium hydroxide
T=60°C;
参考文献
Bogoslowskii
Zhurnal Obshchei Khimii, 1944 , vol. 14, p. 995
Chem.Abstr., 1945 , p. 4598
反应条件
1.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / 0.17 h / 20 °C
1.2: 8 h / 50 °C
2.1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
3.1: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 8 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
2: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 8 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
1.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / 0.17 h / 20 °C
1.2: 8 h / 50 °C
2.1: {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; silver trifluoromethanesulfonate / acetonitrile; water / 10 h / 80 °C / |Inert atmosphere
3.1: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile; water / 8 h / 28 °C / |Inert atmosphere
View Scheme
参考文献
Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung
Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817
反应条件
1: 80 percent / CH2Cl2 / 24 h / Ambient temperature
2: 82 percent / diethyl ether / 5 - 10 °C / Irradiation
View Scheme
参考文献
Chien, Chun-Sheng; Kawasaki, Tomomi; Sakamoto, Masanori; Tamura, Yasumitsu; Kita, Yasuyuki
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2743 - 2749
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Dupont; Germain
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1946 , vol. 223, p. 743
Bulletin de la Societe Chimique de France, 1947 , p. 526,527, 528
