N-苄基-L-脯氨酸乙酯合成路线 （共 18 条）
反应条件
potassium carbonate in acetone T=25°C; 12 h;
参考文献
Organic Letters, , vol. 15, # 13 p. 3378 - 3380
参考文献
Tetrahedron Asymmetry, , vol. 23, # 10 p. 795 - 801
参考文献
Mloston, Grzegorz; Pieczonka, Adam M.; Wroblewska, Aneta; Linden, Anthony; Heimgartner, Heinz
Heterocycles, 2012 , vol. 86, # 1 p. 343 - 356
反应条件
1: thionylchloride / -30 deg C to Rt, reflux, 1 h 2: triethylamine / ethanol / 4 h / Heating View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
反应条件
triethylamine in ethanol 4 h; Heating; Yield given;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 97, # 8-9 p. 691 - 704
反应条件
N,N-bis-2-(hydroxyethyl)-2-amino ethane sulfonic acid; lipase from Bacillus thermocatenulanatus in water T=40°C; pH=7.20; Enzyme kinetics;
参考文献
Liu, Andrew Man Fai; Somers, Neil A.; Kazlauskas, Romas J.; Brush, Terry S.; Zocher, Frank; Enzelberger, Markus M.; Bornscheuer, Uwe T.; Horsman, Geoff P.; Mezzetti, Alessandra; Schmidt-Dannert, Claudia; Schmid, Rolf D.
Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 545 - 556
反应条件
1: 75 percent / diethyl ether / 2 h / Heating 2: 90 percent / H2 / 10 percent Pd/C / ethanol / Ambient temperature View Scheme
参考文献
Enders, Dieter; Kipphardt, Helmut; Gerdes, Peter; Brena-Valle, Leonardo J.; Bhushan, Vidya
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 8-9 p. 691 - 704
反应条件
1: 75 percent / diethyl ether / 2 h / Heating 2: 72 percent / Li, NH3 / diethyl ether; tetrahydrofuran / 3 h / -45 °C 3: 91 percent / H2 / 10 percent Pd/C / ethanol / 3 h / Heating View Scheme
参考文献
Enders, Dieter; Kipphardt, Helmut; Gerdes, Peter; Brena-Valle, Leonardo J.; Bhushan, Vidya
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 8-9 p. 691 - 704
反应条件
1.1: magnesium / tetrahydrofuran / 20 °C 1.2: 92 percent / tetrahydrofuran / 20 °C 2.1: 92 percent / H2; acetic acid / Pd(OH)2/C / CH2Cl2; methanol / 20 °C / 760 Torr View Scheme
参考文献
Nakano, Koji; Nozaki, Kyoko; Hiyama, Tamejiro
Journal of the American Chemical Society, 2003 , vol. 125, # 18 p. 5501 - 5510
反应条件
1: 75 percent / diethyl ether / 2 h / Heating 2: 90 percent / H2 / 10 percent Pd/C / ethanol / Ambient temperature View Scheme
参考文献
Enders, Dieter; Kipphardt, Helmut; Gerdes, Peter; Brena-Valle, Leonardo J.; Bhushan, Vidya
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 8-9 p. 691 - 704
