4-氨基-2-甲基-5-(氨甲基)嘧啶合成路线 （共 34 条）
反应条件
ammonia; hydrogen in methanol T=100°C; P=30003 Torr; 5 h; AutoclaveSaturated solutionLarge scale reaction;
参考文献
Zhao, Lei; Ma, Xiao-Dong; Chen, Fen-Er
Organic Process Research and Development, 2012 , vol. 16, # 1 p. 57 - 60
反应条件
sodium hydroxide; water in methanol T=66.84 - 75.84°C; 4.5 h; Product distribution / selectivity;
参考文献
WO2006/79504 A2, ;
Page/Page column 11; 19-20; 24 ;
反应条件
ammonia; Titanium(IV) oxide in toluene T=270°C; 4 h;
参考文献
BASF Aktiengesellschaft
Patent: US6365740 B1, 2002 ;
Location in patent: Example 8 ;
反应条件
hydroxylamine hydrochloride in water
反应条件
sodium hydroxide T=75°C; 3 h; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 17, # 3 p. 427 - 431
反应条件
1: POCl3 / folgendes Erhitzen mit aethanol.NH3 2: N2H4+H2O 3: KNO2; water; HCl View Scheme
参考文献
Yakugaku Zasshi, , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., , p. 4724
反应条件
1: With copper(l) chloride T=90°C; 16 h; Inert atmosphere; 2: With hydrogenchloride; water T=60°C; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 17, # 3 p. 427 - 431
反应条件
potassium hydroxide; water; bromine
参考文献
Yakugaku Zasshi, , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., , p. 4724
Chemische Berichte, , vol. 70, p. 2035,2044
反应条件
1: N2H4+H2O 2: KNO2; water; HCl View Scheme
参考文献
Yakugaku Zasshi, , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., , p. 4724
