5-氯-3-甲基-1-苯基吡唑-4-甲醛合成路线 (共 23 条)
反应条件
bis(trichloromethyl) carbonate in chlorobenzene T=130°C; Vilsmeier formylation; 7 h;
参考文献
Zhong, Weihui; Chen, Xiao; Shen, Yanyan
Journal of Chemical Research, 2010 , # 7 p. 370 - 374
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7024 - 7028
反应条件
trichlorophosphate T=70°C; Vilsmeier-Haack reaction; 7 h;
参考文献
Barreiro, Eliezer J.; Camara, Celso A.; Verli, Hugo; Brazil-Mas, Leonora; Castro, Newton G.; Cintra, Wagner M.; Aracava, Yasco; Rodrigues, Carlos R.; Fraga, Carlos A. M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 7 p. 1144 - 1152
反应条件
trichlorophosphate in methanol; dichloromethane; N,N-dimethyl-formamide
反应条件
ammonia; trichlorophosphate in water
反应条件
1: sulfuric acid / 0.13 h / Microwave irradiation; neat (no solvent) 2: trichlorophosphate / 1.5 h / Reflux; Inert atmosphere View Scheme
参考文献
Chemistry of Heterocyclic Compounds, , vol. 46, # 12 p. 1500 - 1508
反应条件
trifluoroacetic acid Duff Aldehyde Synthesis; 6 h; Reflux; chemoselective reaction;
参考文献
De Oliveira; Mairink; Pazini; Liao; Viegas Jr.; Cunha; Oliveira; Paz Jr.; Eberlin; Menegatti, Ricardo
Synthetic Communications, 2013 , vol. 43, # 12 p. 1633 - 1639
反应条件
1: hydrogenchloride / ethanol; water 2: sodium hydroxide / ethanol; water 3: trichlorophosphate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7024 - 7028
反应条件
1: sodium hydroxide / ethanol; water 2: trichlorophosphate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7024 - 7028
参考文献
Asian Journal of Chemistry, , vol. 24, # 7 p. 2972 - 2974