4-乙氧基-3-硝基吡啶.盐酸盐合成路线 （共 8 条）
反应条件
1: 70 percent / fuming HNO3, fuming H2SO4 / 1,2-dichloro-ethane / 7 h / 80 - 82 °C 2: PCl5 / 1) PCl5, 1,2-dichloroethane, reflux, 6 h , 2) reflux, 1 h View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 3 p. 669 - 672
反应条件
phosphorus pentachloride 1) PCl5, 1,2-dichloroethane, reflux, 6 h , 2) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 3 p. 669 - 672
反应条件
hydrazine in acetonitrile 5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 3 p. 669 - 672
反应条件
1: 90 percent / N2H4 / acetonitrile / 5 h / Heating 2: 94 percent / H2 / Raney Ni / ethanol / 2 h / 20 - 50 °C / 3102.9 Torr View Scheme
参考文献
Campbell; Greene; Lavagnino; et al.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 669 - 672
反应条件
ammonium acetate; triethylamine in water; ethyl acetate
反应条件
ammonium acetate in water 7 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 3 p. 669 - 672
反应条件
in ethanol 18 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 3 p. 669 - 672
反应条件
sodium hydrogencarbonate in water; ethyl acetate
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/46678 A1, 2005 ;
Location in patent: Page/Page column 74 ;
WO 2005/046678 A1
