N,N-二苄基甘氨酸甲酯合成路线 （共 13 条）
反应条件
palladium 10 on activated carbon; hydrogen; 1-n-butyl-3-methylimidazolium tetrafluoroborate in methanol T=20°C; P=760.051 Torr; 12 h;
参考文献
Choi, Jin Kyu; Jeon, Byung Sun; Cho, Jong Hyun; Kim, B. Moon
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 3 p. 735 - 738
反应条件
1: glycine methylester hydrochloride With N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=0°C; 1 h; Inert atmosphere;
2: benzyl bromide in N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
Aspin, Sam; Goutierre, Anne-Sophie; Larini, Paolo; Jazzar, Rodolphe; Baudoin, Olivier
Angewandte Chemie - International Edition, 2012 , vol. 51, # 43 p. 10808 - 10811
Angewandte Chemie, 2012 , vol. 124, # 43 p. 10966 - 10969
反应条件
lithium hydroxide; 4 A molecular sieve in N,N-dimethyl-formamide
T=20°C;
参考文献
Cho, Jong Hyun; Kim, B.Moon
Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1273 - 1276
反应条件
sulfuric acid in 1,2-dichloro-ethane
26 h; Heating;
参考文献
Guanti, Giuseppe; Banfi, Luca; Narisano, Enrica; Scolastico, Carlo
Tetrahedron, 1988 , vol. 44, # 12 p. 3671 - 3684
反应条件
tetrakis(triphenylphosphine) palladium(0); caesium carbonate in tetrahydrofuran
T=110°C; 8 h;
参考文献
Sole, Daniel; Serrano, Olga
Journal of Organic Chemistry, 2010 , vol. 75, # 18 p. 6267 - 6270
反应条件
indium in tetrahydrofuran
T=40°C; 16 h; Yields of byproduct given;
参考文献
Bossard, Fabienne; Dambrin, Valery; Lintanf, Valeie; Beuchet, Pierre; Mosset, Paul
Tetrahedron Letters, 1995 , vol. 36, # 34 p. 6055 - 6058
反应条件
indium in tetrahydrofuran
26 h; Ambient temperature; Yields of byproduct given;
参考文献
Bossard, Fabienne; Dambrin, Valery; Lintanf, Valeie; Beuchet, Pierre; Mosset, Paul
Tetrahedron Letters, 1995 , vol. 36, # 34 p. 6055 - 6058
反应条件
potassium carbonate in water
3 h; Heating;
参考文献
Ordonez, Mario; Gonzalez-Morales, Angelina; Ruiz, Cesar; De La Cruz-Cordero, Ricardo; Fernandez-Zertuche, Mario
Tetrahedron Asymmetry, 2003 , vol. 14, # 13 p. 1775 - 1779
反应条件
oxygen
1.) irradiation, 10.5 h, 2.) 46 h; Yield given. Multistep reaction;
参考文献
Hegedus,L.S.; De Weck,G.; D'Andrea,S.
Journal of the American Chemical Society, 1988 , vol. 110, p. 2122
反应条件
triethylamine in acetonitrile
参考文献
Gray, Brian D.; Jeffs, Peter W.
Journal of the Chemical Society, Chemical Communications, 1987 , # 18 p. 1329 - 1330
