1,2,3,4-四氢咔唑合成路线 （共 202 条）
反应条件
potassium hydrogensulfate; silica gel 0.0138333 h; microwave irradiation;
参考文献
Kapoor, Kamal K.; Ganai, Bilal A.; Kumar, Satish; Andotra, Charanjeet S.
Synthetic Communications, 2006 , vol. 36, # 18 p. 2727 - 2735
反应条件
PhMe2SiLi in tetrahydrofuran 3 h;
参考文献
Fleming, Ian; Frackenpohl, Jens; Ila, Hiriyakkanavar
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1229 - 1235
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 2 h;
参考文献
Scott, Tricia L.; Burke, Nicholas; Carrero-Martinez, Grissell; Soederberg, Bjoern C.G.
Tetrahedron, 2007 , vol. 63, # 5 p. 1183 - 1190
反应条件
[(IPr)Pd(acac)Cl]; potassium tert-butylate; magnesium sulfate in toluene T=100°C; 12 h; Inert atmosphere;
参考文献
Jin, Zhong; Guo, Su-Xian; Qiu, Ling-Ling; Wu, Gui-Ping; Fang, Jian-Xin
Applied Organometallic Chemistry, 2011 , vol. 25, # 7 p. 502 - 507
反应条件
L-(+)-tartaric acid-urea melt T=70°C; Fischer Indole Synthesis; 0.25 h;
参考文献
Gore, Sangram; Baskaran, Sundarababu; Koenig, Burkhard
Organic Letters, 2012 , vol. 14, # 17 p. 4568 - 4571
反应条件
hydrogen; palladium on activated charcoal in methanol P=735.508 Torr; 0.75 h;
参考文献
Banwell, Martin G.; Kelly, Brian D.; Kokas, Okanya J.; Lupton, David W.
Organic Letters, 2003 , vol. 5, # 14 p. 2497 - 2500
反应条件
hydrogen; toluene-4-sulfonic acid; [rhodium(I)(carbonyl)2(acetylacetonate)] in 1,4-dioxane T=100°C; P=52504.2 Torr; 24 h;
参考文献
Linnepe, Petra; Schmidt, Axel M.; Eilbracht, Peter
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 302 - 313
反应条件
1: 2-iodo benzoic acid With sodium azide; benzyl chloroformate; sodium t-butanolate in N,N-dimethyl-formamide T=75°C; 5 h; 2: 4-benzyloxybutyraldehyde With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate in N,N-dimethyl-formamide T=120°C; 16 h; Further stages.;
参考文献
Leogane, Olivier; Lebel, Helene
Angewandte Chemie - International Edition, 2008 , vol. 47, # 2 p. 350 - 352
反应条件
sodium tetrahydroborate in ethanol T=45 - 50°C; 17 h;
参考文献
Kukushkin; Ivanov; Alekseeva; Levina; Kobrakov; Grigor'ev; Granika
Russian Chemical Bulletin, 2005 , vol. 54, # 8 p. 1887 - 1891
反应条件
[S-BINAP]PdBr2; hydrogen in dichloromethane T=120°C; P=41372.9 Torr; 24 h; Autoclave;
参考文献
Cabrera; Sharma; Ayala; Rubio-Perez; Amezquita-Valencia, Manuel
Tetrahedron Letters, 2011 , vol. 52, # 50 p. 6758 - 6762
