4,4-二甲氧基-2,5-环己二烯-1-酮合成路线 （共 49 条）
反应条件
1: 100 percent / <(Ph3P)CuH>6 / benzene / 0.5 h / Ambient temperature 2: 80 percent / silica gel View Scheme
参考文献
Koenig, Thomas M.; Daeuble, John F.; Brestensky, Donna M.; Stryker, Jeffrey M.
Tetrahedron Letters, 1990 , vol. 31, # 23 p. 3237 - 3240
反应条件
in tetrahydrofuran T=180°C; 12 h; other solvents (CH3CN,EtOH,MeOH), other temp.(190,165 deg C); KineticsMechanismRate constant;
参考文献
Capparelli, Michael P.; Swenton, John S.
Journal of Organic Chemistry, 1987 , vol. 52, # 24 p. 5360 - 5364
反应条件
thien-2-yl(cyano)copper lithium Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Caprio, Vittorio; Mann, John
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 19 p. 3151 - 3155
反应条件
N,N'-dimethylhydrazine bishydrochloride in acetonitrile 0.5 h; Reflux; Reagent/catalyst; regioselective reaction;
参考文献
Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Green, Riana; Li, Sihan; Zheng, Shengping
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 18 p. 2854 - 2858
反应条件
N,N'-dimethylhydrazine bishydrochloride in acetonitrile 1 h; Reflux; regioselective reaction;
参考文献
Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Green, Riana; Li, Sihan; Zheng, Shengping
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 18 p. 2854 - 2858
反应条件
1: hexafluoroisopropyl alcohol; 2,3,4,5,6-pentafluorobenzoic acid / dichloromethane / 0.17 h / 20 °C 2: toluene-4-sulfonic acid / toluene / |Reflux View Scheme
参考文献
Hu, Yinjun; Kamitanaka, Tohru; Mishima, Yusuke; Dohi, Toshifumi; Kita, Yasuyuki
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5530 - 5543
反应条件
1: 1) n-butyllithium / 1) THF, hexane, -78 deg C, 0.5 h, then 0 deg C, 1.5 h, 2) THF, -78 deg C, 4 h 2: 1) (CF3CO)2O, CF3CO2H, H2SO4, 2) K2CO3 / 1) reflux, 4.5 h, 2) CH3OH View Scheme
参考文献
Hart, David J.; Kim, Adrienne; Krishnamurthy, Ramanarayanan; Merriman, Gregory H.; Waltos, Anne-Marie
Tetrahedron, 1992 , vol. 48, # 38 p. 8179 - 8188
反应条件
(i), (ii) Pd-C, H2; Multistep reaction;
参考文献
Taylor,E.C. et al.
Journal of Organic Chemistry, 1978 , vol. 43, # 22 p. 4385 - 4387
反应条件
in tetrahydrofuran; hexane T=-78°C; 1 h;
参考文献
Parker, Kathlyn A.; Coburn, Craig A.; Koh, Yung-hyo
Journal of Organic Chemistry, 1995 , vol. 60, # 9 p. 2938 - 2941
反应条件
trimethylsilyl bromide in acetonitrile T=20°C; 0.5 h; regioselective reaction;
参考文献
Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Green, Riana; Li, Sihan; Zheng, Shengping
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 18 p. 2854 - 2858
