反应条件
1.1: triethylamine / 1,2-dichloro-ethane / 20 °C 2.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / acetonitrile / 35 °C / sodium phosphate buffer 2.2: 20 °C 3.1: diazomethyl-trimethyl-silane / dichloromethane; diethyl ether / 0.58 h / 20 °C View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; DHAR, T.G. Murali; XIAO, Hai-Yun; WATTERSON, Scott Hunter; KO, Soo S.; DYCKMAN, Alaric J.; LANGEVINE, Charles M.; DAS, Jagabandhu; CHERNEY, Robert J.
Patent: WO2011/59784 A1, 2011 ;
WO 2011/059784 A1