lithium aluminium tetrahydride in tetrahydrofuran Inert atmosphere;

<b>Multi-step reaction with 2 steps<br /> </b>1: 91 percent / toluene / 48 h / 75 - 85 &deg;C<br />2: 80 percent / KF/Al₂O₃ / acetonitrile / 48 h / Ambient temperature<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343346', constants.ctx, '0')">potassium phosphate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '20988257', constants.ctx, '0')">Pd((CH₃)2C₆H₃NC(CH₃)CHC(CH₃)NC₆H₃(CH₃)2)(CH₃)(P(CH₂CH₃)3)</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3570983', constants.ctx, '0')">tetrabutylammomium bromide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />T=85&deg;C;&nbsp;Heck coupling;&nbsp;6&nbsp;h;&nbsp;&nbsp;optical yield given as percent destereoselective reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: (i) Zn, (ii) POCl₃, (iii) aq. NaOH<br />2: H₂SO₄ / benzene / Heating<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4122952', constants.ctx, '0')">sodium hydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8190416', constants.ctx, '0')">mineral oil</a> <br />T=-78 - 20&deg;C;&nbsp;3&nbsp;h;&nbsp;<br /> &nbsp;