1: propyl bromide With magnesium in diethyl ether 2: succinic acid anhydride With copper(l) iodide in diethyl ether T=-20 - 20°C; 3: With hydrogenchloride; water in diethyl ether 0.5 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/92566 A1, 2009 ;
Location in patent: Page/Page column 67-68 ;
hydrogenchloride T=160 - 170°C; Erhitzen im geschlossenen Rohr;
参考文献
Bulletin de la Societe Chimique de France, , vol. <3> 27, p. 1083,1088, 1089
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 132, p. 701,703