4-(2-环丙基-4-乙基-5-嘧啶)苯甲腈合成路线 (共 2 条)
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in acetonitrile
5 h; Heating / reflux;
参考文献
AMGEN INC.
Patent: WO2007/2701 A2, 2007 ;
Location in patent: Page/Page column 52-54 ;
WO 2007/002701 A2
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane
7 h; Heating / reflux;
参考文献
AMGEN INC.
Patent: WO2007/2701 A2, 2007 ;
Location in patent: Page/Page column 52; 54 ;
WO 2007/002701 A2