3-氨基-5-(4-氯苯基)噻吩-2-羧酸乙酯合成路线 （共 6 条）
反应条件
sodium ethanolate in ethanol 0.5 h;
参考文献
Shastin; Golubinskii; Lenkova; Balenkova; Nenaidenko
Russian Journal of Organic Chemistry, 2006 , vol. 42, # 2 p. 238 - 240
反应条件
Na2S*9H2O in N,N-dimethyl-formamide T=60°C; 3 h;
参考文献
Synthesis, , # 8 art. no. Z54010SS, p. 1314 - 1318
反应条件
1.1: trichlorophosphate / 5 h / 60 °C 1.3: Reflux 2.1: Na2S*9H2O / N,N-dimethyl-formamide / 3 h / 60 °C View Scheme
参考文献
Synthesis, , # 8 art. no. Z54010SS, p. 1314 - 1318
反应条件
sodium 1.) methanol or ethanol, room temp., 2.) reflux, 10 min; Yield given. Multistep reaction;
参考文献
Synthesis, , # 3 p. 275 - 276
反应条件
1: With potassium hydroxide in ethanol; water 4 h; Reflux; 2: With phosphoric acid in water
参考文献
Synthesis, , # 15 art. no. Z07410SS, p. 2543 - 2546
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 91 - 96
