1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; bis(triphenylphosphine)palladium(II)-chloride in N,N-dimethyl-formamide T=140°C; 15 h;

2: 93 percent / BBr3 / CH2Cl2 / 1) -78 deg C, 1 h, 2) RT, 2 h 3: 95 percent / 2,6-lutidine / CH2Cl2 / 1 h / -30 - 0 °C 4: 60 percent / LiCl, DBU / bis(triphenylphosphine)palladium(II) chloride / dimethylformamide / 15 h / 140 °C View Scheme

2: 93 percent / BBr3 / CH2Cl2 / 1) -78 deg C, 1 h, 2) RT, 2 h 3: 95 percent / 2,6-lutidine / CH2Cl2 / 1 h / -30 - 0 °C 4: 60 percent / LiCl, DBU / bis(triphenylphosphine)palladium(II) chloride / dimethylformamide / 15 h / 140 °C View Scheme

1: 95 percent / 2,6-lutidine / CH2Cl2 / 1 h / -30 - 0 °C 2: 60 percent / LiCl, DBU / bis(triphenylphosphine)palladium(II) chloride / dimethylformamide / 15 h / 140 °C View Scheme

1: 93 percent / BBr3 / CH2Cl2 / 1) -78 deg C, 1 h, 2) RT, 2 h 2: 95 percent / 2,6-lutidine / CH2Cl2 / 1 h / -30 - 0 °C 3: 60 percent / LiCl, DBU / bis(triphenylphosphine)palladium(II) chloride / dimethylformamide / 15 h / 140 °C View Scheme